Bridges James W, Greim Helmut, van Leeuwen Kees, Stegmann Rainer, Vermeire Theo, den Haan Klaas
University of Surrey, United Kingdom.
Technische Universität München, Germany.
Regul Toxicol Pharmacol. 2023 Mar;139:105356. doi: 10.1016/j.yrtph.2023.105356. Epub 2023 Feb 8.
A fully integrated Chemicals Strategy for Sustainability (CSS) in respect of chemicals is crucial and must include: • An objective evaluation of the present situation including impacts of 'chemicals of concern' throughout their life cycle, that incorporates sustainability issues. • A framework that facilitates innovation of chemistry-based approaches to tackle each of the key sustainability issues. The EU CSS only addresses adverse impacts and mainly focusses on one aspect of risk assessment, the hazard to humans from individual industrial chemicals. The proposal removes consideration of the nature and amount of exposure, which is a critical determinant of risk. It can be presumed that this is solely to simplify, and hence speed up, regulatory decisions thereby enabling more chemicals to be assessed. The linkage of this proposed approach to address any of the major sustainability issues, such as environmental pollutants is obscure. For example, the well-recognised environmental problems caused by polymers such as plastics are not considered. The proposed change in the assessment methodology lacks any scientific justification and fails to address the sustainability issues the EU and the rest of the world are facing. The authors critically discuss a comprehensive innovative evaluation methodology for the impact of chemicals.
制定一项全面整合的化学品可持续发展战略（CSS）至关重要，该战略必须包括：• 对现状进行客观评估，包括 “关注化学品” 在其整个生命周期中的影响，并纳入可持续性问题。• 一个促进基于化学方法创新的框架，以解决每个关键的可持续性问题。欧盟的化学品可持续发展战略仅涉及不利影响，且主要侧重于风险评估的一个方面，即单个工业化学品对人类的危害。该提案未考虑接触的性质和数量，而这是风险的关键决定因素。可以推测，这样做纯粹是为了简化并因此加快监管决策，从而能够评估更多化学品。这种提议的方法与解决任何重大可持续性问题（如环境污染物）之间的联系并不明确。例如，未考虑塑料等聚合物造成的广为人知的环境问题。评估方法的提议变更缺乏任何科学依据，也未能解决欧盟和世界其他地区所面临的可持续性问题。作者批判性地讨论了一种针对化学品影响的全面创新评估方法。
