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Dysregulation of developmental and cell type-specific expression of glycoconjugates on hematopoietic cells: a new characteristic of myelodysplastic neoplasms (MDS).

作者信息

van Spronsen Margot F, Horrevorts Sophie, Cali Claudia, Westers Theresia M, Van Gassen Sofie, Saeys Yvan, van Vliet Sandra J, van Kooyk Yvette, van de Loosdrecht Arjan A

机构信息

Amsterdam UMC location Vrije Universiteit Amsterdam, Departement of Hematology, Cancer Center Amsterdam, Boelelaan, 1117, Amsterdam, The Netherlands.

Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Boelelaan, 1117, Amsterdam, The Netherlands.

出版信息

Leukemia. 2023 Mar;37(3):702-707. doi: 10.1038/s41375-022-01784-x. Epub 2023 Feb 9.

DOI:10.1038/s41375-022-01784-x
PMID:36759685
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9991906/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0e2/9991906/3cba44c78a81/41375_2022_1784_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0e2/9991906/e1a5fafed3ca/41375_2022_1784_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0e2/9991906/3cba44c78a81/41375_2022_1784_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0e2/9991906/e1a5fafed3ca/41375_2022_1784_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0e2/9991906/3cba44c78a81/41375_2022_1784_Fig2_HTML.jpg

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本文引用的文献

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Glycosphingolipid-Glycan Signatures of Acute Myeloid Leukemia Cell Lines Reflect Hematopoietic Differentiation.糖脂-聚糖特征可反映急性髓系白血病细胞系的造血分化。
J Proteome Res. 2022 Apr 1;21(4):1029-1040. doi: 10.1021/acs.jproteome.1c00911. Epub 2022 Feb 15.
2
Galactosyl carbohydrate residues on hematopoietic stem/progenitor cells are essential for homing and engraftment to the bone marrow.半乳糖糖残基在造血干/祖细胞上对于归巢和植入骨髓是必需的。
Sci Rep. 2019 May 9;9(1):7133. doi: 10.1038/s41598-019-43551-6.
3
Distinctive Surface Glycosylation Patterns Associated With Mouse and Human CD4 Regulatory T Cells and Their Suppressive Function.
与小鼠和人类CD4调节性T细胞及其抑制功能相关的独特表面糖基化模式
Front Immunol. 2017 Aug 21;8:987. doi: 10.3389/fimmu.2017.00987. eCollection 2017.
4
Characterizing cell subsets using marker enrichment modeling.使用标志物富集模型对细胞亚群进行表征。
Nat Methods. 2017 Mar;14(3):275-278. doi: 10.1038/nmeth.4149. Epub 2017 Jan 30.
5
ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3β/β-catenin signaling pathway.ST6Gal-I过表达通过PI3K/Akt/GSK-3β/β-连环蛋白信号通路促进前列腺癌进展。
Oncotarget. 2016 Oct 4;7(40):65374-65388. doi: 10.18632/oncotarget.11699.
6
Graphical representation of clinical outcomes for patients with myelodysplastic syndromes.骨髓增生异常综合征患者临床结局的图形表示。
Leuk Lymphoma. 2016;57(1):17-20. doi: 10.3109/10428194.2015.1061191. Epub 2015 Oct 5.
7
In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.配对的结直肠癌组织和非致瘤组织的深度N-糖组分析揭示了癌症、分期和表皮生长因子受体(EGFR)特异性蛋白N-糖基化。
Glycobiology. 2015 Oct;25(10):1064-78. doi: 10.1093/glycob/cwv042. Epub 2015 Jun 17.
8
Protein glycosylation in cancer.癌症中的蛋白质糖基化
Annu Rev Pathol. 2015;10:473-510. doi: 10.1146/annurev-pathol-012414-040438.
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FlowSOM: Using self-organizing maps for visualization and interpretation of cytometry data.FlowSOM:使用自组织映射对细胞计数数据进行可视化和解释
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