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[1例经体外循环成功切除侵犯右心房的肝细胞癌]

[A Case of Hepatocellular Carcinoma Extending into Right Atrium Was Resected Successfully Using Cardiopulmonary Bypass].

作者信息

Sakai Kenji, Gotoh Kunihito, Toshiyama Reishi, Kawai Kenji, Takahashi Yusuke, Hamakawa Takuya, Doi Takashi, Takeno Atsushi, Kato Takeshi, Takami Kouji, Hirao Motohiro

机构信息

Dept. of Surgery, National Hospital Organization Osaka National Hospital.

出版信息

Gan To Kagaku Ryoho. 2023 Jan;50(1):99-101.

Abstract

A 59-year-old male was referred to our hospital for a thorough examination of liver function abnormality in the background of chronic hepatitis C. Abdominal contrast-enhanced CT showed multiple tumors in the right lobe of the liver, and an 8 cm tumor occupying S7, a tumor thrombus extending from the right hepatic vein to the inferior vena cava, and a tumor thrombus in the right branch of the portal vein. The patient was diagnosed with hepatocellular carcinoma, cT4N0M0, cStage ⅣA. After 5 courses of hepatic arterial infusion therapy, the intrahepatic lesion was significantly reduced, but micropulmonary metastasis appeared, and the tumor thrombus in the inferior vena cava increased to the thoracic inferior vena cava and just below the tricuspid valve. The patient had difficulty blocking blood flow in the inferior vena cava in the pericardial sac. The patient underwent right hepatectomy, tumor thrombus resection of the inferior vena cava, combined resection of the inferior vena cava, and bovine pericardial patch reconstruction under artificial cardiopulmonary support. He was discharged on the 23rd day after surgery and has been under outpatient observation for 16 months while receiving molecular-targeted drugs for lung metastasis.

摘要

一名59岁男性因慢性丙型肝炎背景下的肝功能异常被转诊至我院进行全面检查。腹部增强CT显示肝脏右叶有多个肿瘤,一个8厘米的肿瘤占据S7段,一个肿瘤血栓从右肝静脉延伸至下腔静脉,门静脉右支有一个肿瘤血栓。该患者被诊断为肝细胞癌,cT4N0M0,c期ⅣA。经过5个疗程的肝动脉灌注治疗后,肝内病变明显缩小,但出现了微肺转移,下腔静脉的肿瘤血栓延伸至胸段下腔静脉并位于三尖瓣下方。患者在心包囊内难以阻断下腔静脉血流。患者接受了右肝切除术、下腔静脉肿瘤血栓切除术、下腔静脉联合切除术,并在体外循环支持下进行了牛心包补片重建。患者术后第23天出院,在接受针对肺转移的分子靶向药物治疗的同时,已接受门诊观察16个月。

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