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环境温度对“自助餐”喂养大鼠能量平衡、饮食诱导产热及棕色脂肪活性的影响。

Influence of environmental temperature on energy balance, diet-induced thermogenesis and brown fat activity in 'cafeteria'-fed rats.

作者信息

Rothwell N J, Stock M J

机构信息

Department of Physiology, St. George's Hospital Medical School, Tooting, London.

出版信息

Br J Nutr. 1986 Jul;56(1):123-9. doi: 10.1079/bjn19860092.

DOI:10.1079/bjn19860092
PMID:3676188
Abstract
  1. Young male rats were fed on a pelleted stock diet or a variety of palatable food items ('cafeteria' diet) and housed at 24 degrees or 29 degrees. 2. 'Cafeteria' feeding at the lower temperature stimulated energy intake, gain and expenditure, but reduced energetic efficiency such that over 70% of the excess intake was expended. 3. Housing at 29 degrees suppressed intake and expenditure in animals on both diets, but to a greater extent in 'cafeteria'-fed rats and energetic efficiency was greater than control values at this higher temperature. 4. The thermogenic capacity of brown fat (mitochondrial purine nucleotide binding) was increased by 'cafeteria' feeding, but was suppressed in animals kept at 29 degrees. 5. The results demonstrate that diet-induced thermogenesis is inhibited by high environmental temperatures.
摘要
  1. 给年轻雄性大鼠喂食颗粒状常规饲料或多种美味食物(“自助式”饮食),并将其饲养在24摄氏度或29摄氏度的环境中。2. 在较低温度下采用“自助式”喂养方式会刺激能量摄入、增加和消耗,但会降低能量效率,以至于超过70%的额外摄入能量被消耗掉。3. 在29摄氏度环境中饲养会抑制两种饮食喂养的动物的摄入量和消耗量,但对“自助式”喂养的大鼠抑制作用更大,且在这个较高温度下能量效率高于对照值。4. “自助式”喂养会增加棕色脂肪的产热能力(线粒体嘌呤核苷酸结合),但在饲养于29摄氏度环境中的动物中该能力受到抑制。5. 结果表明,环境温度过高会抑制饮食诱导的产热。

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