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食物如药:如何影响肠道微生物组并改善肠易激综合征患者的症状。

Food as Medicine: How to Influence the Microbiome and Improve Symptoms in Patients with Irritable Bowel Syndrome.

机构信息

Department of Medicine, University of Miami, Miami, FL, USA.

Division of Digestive Diseases, Emory University, Atlanta, GA, USA.

出版信息

Curr Gastroenterol Rep. 2023 Mar;25(3):52-60. doi: 10.1007/s11894-023-00861-0. Epub 2023 Feb 10.

Abstract

PURPOSE OF REVIEW

This review highlights effects of dietary interventions on the gut microbiome and gastrointestinal symptoms in those with irritable bowel syndrome (IBS).

RECENT FINDINGS

It is hypothesized that gut dysbiosis factors into the pathophysiology of IBS. Various diets that influence the microbiome and intestinal physiology may have therapeutic properties. At present, data suggests that implementation of personalized dietary interventions have a mixed, but overall positive effect on the gut microbiome and IBS symptoms. The effect of dietary modification on the gut microbiome and GI symptoms in patients with IBS is a topic that has garnered interest due to the increasing prevalence of IBS and heightened awareness of the importance of gut health. The composition of the gut microbiome may be modulated by promoting fiber intake and implementation of exclusionary diets and dietary supplements; however, additional studies are needed to provide evidence-based guidelines in this patient population.

摘要

目的综述

本文重点介绍饮食干预对肠易激综合征(IBS)患者肠道微生物组和胃肠道症状的影响。

最新发现

目前认为,肠道菌群失调是 IBS 发病机制的一个因素。影响微生物组和肠道生理的各种饮食可能具有治疗特性。目前的数据表明,个性化饮食干预的实施对肠道微生物组和 IBS 症状有混合的、但总体积极的影响。由于 IBS 的发病率不断上升,以及人们对肠道健康重要性的认识不断提高,饮食改变对 IBS 患者肠道微生物组和胃肠道症状的影响已成为一个备受关注的话题。通过促进纤维摄入、实施排除性饮食和膳食补充剂,可以调节肠道微生物组的组成;然而,仍需要更多的研究为这一患者群体提供基于证据的指南。

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