de Gamarra M E, Schutz Y, Catzeflis C, Freymond D, Cauderay M, Calame A, Micheli J L, Jequier E
Institute of Physiology, University of Lausanne, Switzerland.
Biol Neonate. 1987;52(4):181-7. doi: 10.1159/000242708.
Changes in the rate of growth and adiposity index (Quetelet index), calculated as weight/(length)2, kg/m2, were monitored from birth to 3 years in 19 premature babies (post-conceptional age 31.2 +/- 2 weeks) who were subjected during rapid growth (16 +/- 4 g/kg.day) to initial metabolic balance studies in the first weeks of life. These studies showed that the rate of fat accretion in these infants (3.3 +/- 0.9 g/kg.day) was substantially greater than that observed in fetuses of the same gestational age (2 g/kg.day) but the adiposity index was lower (9.6 +/- 1 kg/m2) than intrauterine values (11 kg/m2). Since at 6 months of age (corrected for gestational age at birth) the adiposity index was close to normality (103% of standard), the greater rate of fat accretion in early life contributed to progressively restore total body fat in premature babies. It is concluded that despite substantial fat deposition during the first weeks of life, the future evolution of these premature babies is favourable as judged from the normalization of adiposity index within the first 2 years of life.
对19名早产婴儿（孕龄31.2±2周）从出生到3岁期间的生长速率和肥胖指数（体重/身长²，单位为kg/m²）变化进行了监测。这些婴儿在出生后快速生长阶段（体重增加16±4 g/kg·天），在生命的最初几周接受了初始代谢平衡研究。这些研究表明，这些婴儿的脂肪堆积速率（3.3±0.9 g/kg·天）显著高于相同孕周的胎儿（2 g/kg·天），但其肥胖指数（9.6±1 kg/m²）低于子宫内的值（11 kg/m²）。由于在出生后6个月（校正出生时的孕周）时肥胖指数接近正常（为标准值的103%），生命早期较高的脂肪堆积速率有助于早产婴儿逐渐恢复全身脂肪。结论是，尽管在生命的最初几周有大量脂肪沉积，但从这些早产婴儿在出生后2年内肥胖指数恢复正常来看，他们未来的发育情况是良好的。
