Rahima A, Bruce N W
Department of Anatomy and Human Biology, University of Western Australia, Nedlands.
Biol Reprod. 1987 Sep;37(2):277-81. doi: 10.1095/biolreprod37.2.277.
Unilateral ovariectomy was performed on 20 rats 4-5 wk before mating (ULO-B group), and 18 rats 8 days after mating (ULO-A group); 16 rats were maintained as controls. The effects on growth of individual corpora lutea (CL) in the remaining ovary and peripheral blood progestagen concentrations were examined. CL hypertrophy was observed by Day 13 in the ULO-B group and by Day 16 in the ULO-A group. Progesterone and 20 alpha-dihydroprogesterone concentrations were double control values at Day 16 in the ULO-B group, but half the control values in the ULO-A group. The CL hypertrophy and increased progestagen concentrations in the ULO-B group occurred despite crowding due to a doubling of the normal number of CL within the remaining ovary.
在交配前4 - 5周对20只大鼠进行单侧卵巢切除术（ULO - B组），在交配后8天对18只大鼠进行单侧卵巢切除术（ULO - A组）；将16只大鼠作为对照。检测了对剩余卵巢中单个黄体（CL）生长及外周血孕酮浓度的影响。在ULO - B组中，第13天观察到黄体肥大；在ULO - A组中，第16天观察到黄体肥大。在ULO - B组中，第16天孕酮和20α - 双氢孕酮浓度是对照值的两倍，但在ULO - A组中是对照值的一半。尽管由于剩余卵巢中黄体数量加倍导致拥挤，但ULO - B组仍出现了黄体肥大和孕酮浓度升高的情况。
