Society for Cancer Research, Arlesheim, Switzerland.
Scientifc and Regulatory Affairs, Hevert-Arzneimittel GmbH & Co. KG, Nussbaum, Germany.
Homeopathy. 2023 Aug;112(3):152-159. doi: 10.1055/s-0042-1759543. Epub 2023 Feb 10.
Homeopathic complex remedies, composed of several homeopathic medicines in the low potency range, are frequently used in the treatment of a number of common disorders. At the same time, they represent an almost unexplored area of research. Are complex remedies just additive mixtures of the components, or are there interactions between the latter leading to new properties of the complex?
In the present study, we analyzed as an example the simple bi-component complex, 4x - 9x, by means of patterns from evaporated droplets and tested what influences the complex's single compounds have upon the patterns and if there are any interactions. For this purpose, we compared in a series of five experiments patterns from evaporated droplets of the complex, 4x - 9x, and three comparison samples in which one or both of the complex's compounds were replaced by potentized solute. The patterns were photographed and evaluated for their gray-level distribution and texture using the software . The experimental set-up's stability was tested by means of systematic control experiments.
We found that 9x significantly influenced the patterns of 4x, increasing their homogeneity; at the same time, the patterns of 9x combined with solvent were more heterogeneous than those obtained from a control consisting of two pure solvents.
In this phenomenological assay, the complex 4x - 9x does not correspond to a simple addition of the components. The exact nature of the underlying interaction needs to be elucidated in further investigations.
顺势疗法复方药物由几种低浓度的顺势疗法药物组成，常用于治疗许多常见疾病。与此同时，它们是一个几乎未被探索的研究领域。复方药物仅仅是成分的附加混合物，还是后者之间存在相互作用，从而产生复方的新特性？
在本研究中，我们以简单的双组分复方 4x-9x 为例进行分析，通过蒸发液滴的模式，并测试该复方的单一化合物对模式有何影响，以及是否存在相互作用。为此，我们在五个实验系列中比较了复方 4x-9x 的蒸发液滴模式以及三个对照样本的模式，其中一个或两个复方化合物被强溶剂替代。使用软件对图案进行拍照，并评估其灰度分布和纹理。通过系统的对照实验测试了实验装置的稳定性。
我们发现 9x 显著影响 4x 的图案，增加了它们的均匀性；同时，与溶剂结合的 9x 图案比由两个纯溶剂组成的对照样本的图案更不均匀。
在这种现象学测定中，复方 4x-9x 并不对应于成分的简单相加。需要进一步研究阐明潜在相互作用的本质。
