Department of Pediatrics, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Department of Pediatrics, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Pediatr Neonatol. 2023 Jul;64(4):442-449. doi: 10.1016/j.pedneo.2022.09.020. Epub 2023 Jan 25.
To analyze the early electroencephalography (EEG) development of twins and singleton preterm neonates using 5 measurement indicators.
On the 1st and 7th days after birth, EEG monitoring was performed on 102 preterm neonates (62 males, median gestational age 33.15 weeks, IQR 31.00-35.75). The minimum amplitude, maximum amplitude, maximum interburst intervals (IBI), total duration of trace discontinue (TD), maximum duration of single TD, and the Burdjalov score of amplitude-integrated electroencephalography (aEEG) were used to evaluate EEG recordings.
The minimum amplitude of EEG increases with gestational age (GA), while the maximum amplitude decreases, the maximum IBI decreases, and the total duration of TD and the maximum duration of single TD decrease (all p < 0.05). Burdjalov score did not differ significantly between the 1st and 7th days (p = 0.075). There is no significant difference between twins and singleton preterm infants in the five EEG measurement indicators (p > 0.05 for all).
The five EEG measurement indicators can better reflect preterm infants' brain maturation than the Burdjalov score in aEEG. There were no statistical differences in brain maturation between twin and singleton preterm infants.
使用 5 项测量指标分析双胞胎和单胎早产儿的早期脑电图（EEG）发育情况。
对 102 例早产儿（男 62 例，中位胎龄 33.15 周，IQR 31.00-35.75）在出生后第 1 天和第 7 天进行 EEG 监测。采用最小振幅、最大振幅、最大爆发间隔（IBI）、迹线中断总持续时间（TD）、单个 TD 最大持续时间和振幅整合脑电图（aEEG）的 Burdjalov 评分评估脑电图记录。
EEG 的最小振幅随胎龄（GA）增加而增加，最大振幅降低，最大 IBI 降低，TD 总持续时间和单个 TD 最大持续时间降低（均 p<0.05）。Burdjalov 评分在第 1 天和第 7 天之间无显著差异（p=0.075）。双胞胎和单胎早产儿在 5 项 EEG 测量指标上无显著差异（均 p>0.05）。
与 aEEG 中的 Burdjalov 评分相比，这 5 项 EEG 测量指标能更好地反映早产儿的脑成熟度。双胞胎和单胎早产儿的脑成熟度无统计学差异。
