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Toward an effective Staphylococcus vaccine: why have candidates failed and what is the next step?

作者信息

Tsai Chih-Ming, Caldera Jr, Hajam Irshad A, Liu George Y

机构信息

Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.

Department of Pathology and Laboratory Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA, USA.

出版信息

Expert Rev Vaccines. 2023 Jan-Dec;22(1):207-209. doi: 10.1080/14760584.2023.2179486.

DOI:10.1080/14760584.2023.2179486
PMID:36765453
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9972957/
Abstract
摘要

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Cell Host Microbe. 2022 Aug 10;30(8):1163-1172.e6. doi: 10.1016/j.chom.2022.06.006. Epub 2022 Jul 7.
2
Integrating complex host-pathogen immune environments into S. aureus vaccine studies.将复杂的宿主-病原体免疫环境纳入金黄色葡萄球菌疫苗研究。
Cell Chem Biol. 2022 May 19;29(5):730-740. doi: 10.1016/j.chembiol.2022.04.003.
3
Mice with diverse microbial exposure histories as a model for preclinical vaccine testing.具有不同微生物暴露史的小鼠作为临床前疫苗测试的模型。
Cell Host Microbe. 2021 Dec 8;29(12):1815-1827.e6. doi: 10.1016/j.chom.2021.10.001. Epub 2021 Nov 2.
4
Vaccination With Detoxified Leukocidin AB Reduces Bacterial Load in a Staphylococcus aureus Minipig Deep Surgical Wound Infection Model.脱毒白细胞毒素 AB 疫苗接种可降低金黄色葡萄球菌小型猪深部外科感染模型中的细菌负荷。
J Infect Dis. 2022 Apr 19;225(8):1460-1470. doi: 10.1093/infdis/jiab219.
5
Evasion of Immunological Memory by Infection: Implications for Vaccine Design.感染逃避免疫记忆：对疫苗设计的启示。
Front Immunol. 2021 Feb 22;12:633672. doi: 10.3389/fimmu.2021.633672. eCollection 2021.
6
T Cell Immunity and the Quest for Protective Vaccines against Infection.T细胞免疫与寻求抗感染保护性疫苗
Microorganisms. 2020 Dec 6;8(12):1936. doi: 10.3390/microorganisms8121936.
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