Masià-Gridilla Jorge, Gutiérrez-Santamaría Javier, Álvarez-Sáez Iago, Pamias-Romero Jorge, Saez-Barba Manel, Bescós-Atin Coro
Noves Tecnologies i Microcirurgia Craniofacial, Vall d'Hebron Institut de Recerca (VHIR), Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, E-08035 Barcelona, Spain.
Servei de Cirurgia Oral i Maxil·lofacial, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, E-08035 Barcelona, Spain.
Cancers (Basel). 2023 Jan 28;15(3):800. doi: 10.3390/cancers15030800.
A single-center retrospective study was designed to assess the outcomes of autologous fat grafting for improving surgery- and radiotherapy-related sequelae in 40 patients with head and neck cancer. All patients underwent surgical resection of primary tumors and radiotherapy (50-70 Gy) and were followed over 12 months after fat grafting. Eligibility for fat grafting procedures included complete remission after at least 3 years of oncological treatment. The cervical and paramandibular regions were the most frequently treated areas. Injected fat volumes ranged between 7.5 and 120 mL (mean: 23 mL). Esthetic improvement was obtained in 77.5% of patients, being significant in 17.5%, and functional improvement in 89.2%, being significant in 29.7% of patients. Minor complications occurred in three patients. There was a high degree of satisfaction regarding esthetic improvement, global satisfaction, and 92.5% of patients would recommend the procedure. This study confirms the benefits of fat grafting as a volumetric correction reconstructive strategy with successful cosmetic and functional outcomes in patients suffering from sequelae after head and neck cancer treatment.
一项单中心回顾性研究旨在评估自体脂肪移植对40例头颈癌患者改善手术和放疗相关后遗症的效果。所有患者均接受了原发肿瘤的手术切除和放疗（50 - 70 Gy），并在脂肪移植后随访12个月。脂肪移植手术的入选标准包括肿瘤治疗至少3年后完全缓解。颈部和下颌旁区域是最常治疗的部位。注射的脂肪量在7.5至120毫升之间（平均：23毫升）。77.5%的患者获得了美学改善，其中17.5%的改善显著；89.2%的患者获得了功能改善，其中29.7%的改善显著。3例患者出现轻微并发症。患者对美学改善、总体满意度高度满意，92.5%的患者会推荐该手术。这项研究证实了脂肪移植作为一种容积矫正重建策略的益处，对头颈癌治疗后有后遗症的患者具有成功的美容和功能效果。
