Pereira Letícia Jacome, Mohrbacher Sara, Neves Precil Diego Miranda de Menezes, Zacchi Flavia Fernandes Silva, Medeiros Ivan Ucella Dantas, Sato Victor Augusto Hamamoto, Oliveira Érico Souza, Pereira Leonardo Victor Barbosa, Cuvello-Neto Américo Lourenço, Baiocchi Otávio, Chocair Pedro Renato
Internal Medicine Service, Oswaldo Cruz German Hospital, São Paulo 01323-020, Brazil.
Pathology Service, Fleury Laboratory, São Paulo 01431-001, Brazil.
Diagnostics (Basel). 2023 Jan 19;13(3):370. doi: 10.3390/diagnostics13030370.
Primary Effusion Lymphoma is an extremely rare and aggressive subtype of B-cell lymphoma, accounting for only <1% of all cases of this neoplasm. It has a unique clinical presentation because it has a predilection for appearing in body cavities, such as the pleural space, pericardium and peritoneum. It mainly affects immunocompromised individuals and may also affect individuals in the Mediterranean region and in areas endemic for human herpesvirus 8 (HHV-8). Herein, we report the case of an 83-year-old immunocompetent male complaining of coughing, fever and progressive dyspnea for 3 days. His past medical history revealed a recurrent pleural effusion for the last three years, as well as losing weight and malaise. A subsequent investigation revealed a PEL diagnosis of the pleura.
原发性渗出性淋巴瘤是一种极其罕见且侵袭性强的B细胞淋巴瘤亚型，仅占该肿瘤所有病例的不到1%。它具有独特的临床表现，因为它倾向于出现在体腔，如胸腔、心包和腹腔。它主要影响免疫功能低下的个体，也可能影响地中海地区以及人类疱疹病毒8（HHV-8）流行地区的个体。在此，我们报告一例83岁免疫功能正常的男性病例，该患者主诉咳嗽、发热和进行性呼吸困难3天。他的既往病史显示过去三年有复发性胸腔积液，以及体重减轻和身体不适。随后的检查显示胸膜原发性渗出性淋巴瘤的诊断。
