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深度学习模型在子宫腺肌病超声诊断中的应用。

Application of Deep Learning Model in the Sonographic Diagnosis of Uterine Adenomyosis.

机构信息

Division of Gynecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40126 Bologna, Italy.

Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.

出版信息

Int J Environ Res Public Health. 2023 Jan 18;20(3):1724. doi: 10.3390/ijerph20031724.

DOI:10.3390/ijerph20031724
PMID:36767092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9914280/
Abstract

BACKGROUND

This study aims to evaluate the diagnostic performance of Deep Learning (DL) machine for the detection of adenomyosis on uterine ultrasonographic images and compare it to intermediate ultrasound skilled trainees.

METHODS

Prospective observational study were conducted between 1 and 30 April 2022. Transvaginal ultrasound (TVUS) diagnosis of adenomyosis was investigated by an experienced sonographer on 100 fertile-age patients. Videoclips of the uterine corpus were recorded and sequential ultrasound images were extracted. Intermediate ultrasound-skilled trainees and DL machine were asked to make a diagnosis reviewing uterine images. We evaluated and compared the accuracy, sensitivity, positive predictive value, F1-score, specificity and negative predictive value of the DL model and the trainees for adenomyosis diagnosis.

RESULTS

Accuracy of DL and intermediate ultrasound-skilled trainees for the diagnosis of adenomyosis were 0.51 (95% CI, 0.48-0.54) and 0.70 (95% CI, 0.60-0.79), respectively. Sensitivity, specificity and F1-score of DL were 0.43 (95% CI, 0.38-0.48), 0.82 (95% CI, 0.79-0.85) and 0.46 (0.42-0.50), respectively, whereas intermediate ultrasound-skilled trainees had sensitivity of 0.72 (95% CI, 0.52-0.86), specificity of 0.69 (95% CI, 0.58-0.79) and F1-score of 0.55 (95% CI, 0.43-0.66).

CONCLUSIONS

In this preliminary study DL model showed a lower accuracy but a higher specificity in diagnosing adenomyosis on ultrasonographic images compared to intermediate-skilled trainees.

摘要

背景

本研究旨在评估深度学习(DL)机器在经阴道超声图像上检测子宫腺肌病的诊断性能,并将其与中级超声熟练医师进行比较。

方法

前瞻性观察性研究于 2022 年 4 月 1 日至 30 日进行。由一位有经验的超声医师对 100 名生育期患者进行经阴道超声(TVUS)诊断子宫腺肌病。记录子宫体的视频片段并提取连续的超声图像。中级超声熟练医师和 DL 机器被要求通过查看子宫图像做出诊断。我们评估并比较了 DL 模型和中级超声熟练医师对腺肌病诊断的准确性、敏感度、阳性预测值、F1 评分、特异性和阴性预测值。

结果

DL 和中级超声熟练医师诊断子宫腺肌病的准确率分别为 0.51(95%CI,0.48-0.54)和 0.70(95%CI,0.60-0.79)。DL 的敏感度、特异性和 F1 评分分别为 0.43(95%CI,0.38-0.48)、0.82(95%CI,0.79-0.85)和 0.46(0.42-0.50),而中级超声熟练医师的敏感度为 0.72(95%CI,0.52-0.86)、特异性为 0.69(95%CI,0.58-0.79)和 F1 评分为 0.55(95%CI,0.43-0.66)。

结论

在这项初步研究中,与中级熟练医师相比,DL 模型在超声图像上诊断子宫腺肌病的准确性较低,但特异性较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8718/9914280/cd3b700f19a5/ijerph-20-01724-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8718/9914280/cd3b700f19a5/ijerph-20-01724-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8718/9914280/cd3b700f19a5/ijerph-20-01724-g001.jpg

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Uterine Fibroids and Infertility.子宫肌瘤与不孕
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Application of artificial intelligence in gynecologic malignancies: A review.人工智能在妇科恶性肿瘤中的应用:综述
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Application of artificial intelligence to ultrasound imaging for benign gynecological disorders: systematic review.人工智能在良性妇科疾病超声成像中的应用:系统评价
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How Reproducible Are the Ultrasound Features of Adenomyosis Defined by the Revised MUSA Consensus?经修订的MUSA共识所定义的子宫腺肌病超声特征的可重复性如何?
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A stacked machine learning-based classification model for endometriosis and adenomyosis: a retrospective cohort study utilizing peripheral blood and coagulation markers.一种基于堆叠机器学习的子宫内膜异位症和子宫腺肌病分类模型:一项利用外周血和凝血标志物的回顾性队列研究。
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From Diagnosis to Fertility: Optimizing Treatment of Adenomyosis for Reproductive Health.从诊断到生育:优化子宫腺肌病治疗以促进生殖健康
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