Department of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh.
Department of Bone Marrow Transplant, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Int J Environ Res Public Health. 2023 Jan 18;20(3):1786. doi: 10.3390/ijerph20031786.
The prevalence of anemia is high among children and adolescents in low- and middle-income countries because of undernutrition resulting from their poor socioeconomic status and lack of knowledge on proper nutrition. We conducted a systematic review and meta-analysis to determine the prevalence of anemia among children and adolescents aged between 6 months and 19 years in Bangladesh. Databases such as PubMed, Scopus, and Google Scholar were searched to identify the studies that reported the prevalence of anemia among children and adolescents. A total of 24 studies, including the data of 14,062 cases, were included in the systematic review and meta-analysis of the time period between 1997 and 2019. The random-effects model was used to calculate the summary estimates. The protocol was registered with PROSPERO (CRD42021246960). The pooled prevalence of anemia, iron deficiency anemia (IDA), and non-severe and severe anemia were 46.8% [95% CI: 36.0-57.6], 13.6% [95% CI: 8.0-19.2], 56.4% [95% CI: 39.6-73.1] and 0.7% [95% CI: 0.1-1.4], respectively. Prevalence of anemia exhibited the highest among the children aged ≤2 years. Briefly, 91.67% of the studies were of high quality. No significant publication bias was found; however, two outlier studies were detected. The prevalence of anemia among children and adolescents was estimated as high in Bangladesh.
贫血在中低收入国家的儿童和青少年中很常见,这是由于他们贫困的社会经济地位和缺乏适当营养知识导致的营养不良。我们进行了系统评价和荟萃分析,以确定孟加拉国 6 个月至 19 岁儿童和青少年贫血的患病率。检索了 PubMed、Scopus 和 Google Scholar 等数据库,以确定报告儿童和青少年贫血患病率的研究。共有 24 项研究,包括 14062 例病例的数据,被纳入了 1997 年至 2019 年期间的系统评价和荟萃分析。使用随机效应模型计算汇总估计值。该方案已在 PROSPERO(CRD42021246960)中注册。贫血、缺铁性贫血(IDA)、非严重和严重贫血的总患病率分别为 46.8%(95%CI:36.0-57.6)、13.6%(95%CI:8.0-19.2)、56.4%(95%CI:39.6-73.1)和 0.7%(95%CI:0.1-1.4)。贫血的患病率在≤2 岁的儿童中最高。简而言之,91.67%的研究质量较高。未发现显著的发表偏倚,但检测到两项异常值研究。估计孟加拉国儿童和青少年贫血的患病率较高。