Fang F G, Moreau J L, Fields H L
Department of Neurology, University of California, San Francisco 94143.
Brain Res. 1987 Sep 8;420(1):171-4. doi: 10.1016/0006-8993(87)90255-1.
Microinjection of neurotensin into the rat rostroventromedial medulla produces dose-dependent inhibition of the tailflick reflex (ED50 of 2.06 nmol/animal (1.33-3.19)). The peak effect occurs 15-20 min following injection and, at the highest dose used, lasts up to 70 min.
向大鼠延髓头端腹内侧微注射神经降压素可产生剂量依赖性的甩尾反射抑制作用(半数有效剂量为2.06 nmol/动物(1.33 - 3.19))。注射后15 - 20分钟出现最大效应,在所用的最高剂量下,持续长达70分钟。