Lin Y C
Comput Programs Biomed. 1979 Mar;9(2):135-40. doi: 10.1016/0010-468x(79)90026-6.
Reconstruction of the primary indicator-dilution curve is accomplished by exponential curve-fit from a set of points obtained on the downslope of the curve. Curve-fit is simplified by requiring entry of indicator concentrations (Yi) only, where time increments (Xi) are made self-generating in the program. Similarly, calculation of mean transit time requires only the entries of Yi. Stored values supply the needed quantities for calculations of cardiac output and the central blood volume as defined by the injection and the sampling sites. The Texas Instrument TR 52 model hand-held programmable calculator is utilized in this program but it should be adaptable to other programmable calculators. The present program provides a procedure for rapid reconstruction of the primary indicator-dilution curve, and hence calculations of cardiac output, mean transit time and central blood volume.
通过对从曲线下降段获取的一组点进行指数曲线拟合来完成初级指示剂稀释曲线的重建。通过仅要求输入指示剂浓度（Yi）简化曲线拟合，其中时间增量（Xi）在程序中自动生成。同样，平均通过时间的计算仅需要输入Yi。存储的值提供计算心输出量和由注射和采样部位定义的中心血容量所需的量。本程序使用德州仪器TR 52型手持式可编程计算器，但应适用于其他可编程计算器。本程序提供了一种快速重建初级指示剂稀释曲线的方法，从而可以计算心输出量、平均通过时间和中心血容量。
