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Coating Materials to Increase the Stability of Liposomes.

作者信息

Pasarin Diana, Ghizdareanu Andra-Ionela, Enascuta Cristina Emanuela, Matei Catalin Bogdan, Bilbie Catalin, Paraschiv-Palada Luciana, Veres Petronela-Andreea

机构信息

Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie, ICECHIM, 202 Splaiul Independentei, 060021 Bucuresti, Romania.

Facultatea de Stiinta si Ingineria Materialelor, Universitatea Politehnica din Bucuresti, 313 Splaiul Independentei, 060042 Bucharest, Romania.

出版信息

Polymers (Basel). 2023 Feb 3;15(3):782. doi: 10.3390/polym15030782.


DOI:10.3390/polym15030782
PMID:36772080
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10004256/
Abstract

Liposomes carry various compounds with applications in pharmaceutical, food, and cosmetic fields, and the administration route is especially parenteral, oral, or transdermal. Liposomes are used to preserve and release the internal components, thus maintaining the properties of the compounds, the stability and shelf life of the encapsulated products, and their functional benefits. The main problem in obtaining liposomes at the industrial level is their low stability due to fragile phospholipid membranes. To increase the stability of liposomes, phospholipid bilayers have been modified or different coating materials have been developed and studied, both for liposomes with applications in the pharmaceutical field and liposomes in the food field. In the cosmetic field, liposomes need no additional coating because the liposomal formulation is intended to have a fast penetration into the skin. The aim of this review is to provide current knowledge regarding physical and chemical factors that influence stability, coating materials for liposomes with applications in the pharmaceutical and food fields to increase the stability of liposomes containing various sensitive compounds, and absorption of the liposomes and commercial liposomal products obtained through various technologies available on the market.

摘要

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本文引用的文献

[1]
The Role of Cryoprotective Agents in Liposome Stabilization and Preservation.

Int J Mol Sci. 2022-10-18

[2]
Surface-engineered liposomal particles of calcium ascorbate with fenugreek galactomannan enhanced the oral bioavailability of ascorbic acid: a randomized, double-blinded, 3-sequence, crossover study.

RSC Adv. 2021-11-26

[3]
Polymer-Modified Liposomes for Drug Delivery: From Fundamentals to Applications.

Pharmaceutics. 2022-4-2

[4]
Pelargonidin---Glucoside Encapsulated Pectin-Chitosan-Nanoliposomes Recovers Palmitic Acid-Induced Hepatocytes Injury.

Antioxidants (Basel). 2022-3-24

[5]
Methods of Liposomes Preparation: Formation and Control Factors of Versatile Nanocarriers for Biomedical and Nanomedicine Application.

Pharmaceutics. 2022-2-28

[6]
Lipid Nanoparticles as a Promising Drug Delivery Carrier for Topical Ocular Therapy-An Overview on Recent Advances.

Pharmaceutics. 2022-2-27

[7]
A Novel Sprague-Dawley Rat Model Presents Improved NASH/NAFLD Symptoms with PEG Coated Vitexin Liposomes.

Int J Mol Sci. 2022-3-15

[8]
Encapsulation efficiency and oral delivery stability of chitosan-liposome-encapsulated immunoglobulin Y.

J Food Sci. 2022-4

[9]
A sensitive cholesterol electrochemical biosensor based on biomimetic cerasome and graphene quantum dots.

Anal Bioanal Chem. 2022-5

[10]
A Review of Liposomes as a Drug Delivery System: Current Status of Approved Products, Regulatory Environments, and Future Perspectives.

Molecules. 2022-2-17

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