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低水平电离辐射的免疫调节特性可作为治疗 COVID-19 危及生命症状的潜在方法。

The immunomodulatory properties of low-level ionizing radiation as a potential treatment for COVID-19's life-threatening symptoms.

机构信息

Radiation Safety Department, Nuclear and Radiological Safety Research Center, Egyptian Atomic Energy Authority, Cairo, Egypt.

出版信息

Eur J Med Res. 2023 Feb 11;28(1):73. doi: 10.1186/s40001-023-00999-7.

Abstract

Public health experts are looking into the current coronavirus outbreak to see if there are any ways to prevent potentially fatal symptoms. Low-Dose Radiotherapy (LD-RT) induces anti-inflammatory cytokine responses that act as a counterweight to pro-inflammatory cytokines, potentially providing therapeutic benefits for COVID-19-related diseases associated with significant morbidity and mortality. This study will look into positive immuno-radiological reactions to see if they are feasible, practicable, and effective in lowering the critical inflammatory condition of the crucial stage COVID-19. This study aims to investigate the use of low-dose lung radiation in bacterial and viral pneumonia, as well as to provide a treatment plan for COVID-19-associated pneumonia. This article discusses the evidence for and against LD-RT theories in COVID-19 patients. The use of LD-RT at various stages of COVID-19 appears to be beneficial, with fewer side effects than other currently being studied treatments.

摘要

公共卫生专家正在研究当前的冠状病毒爆发,以寻找预防潜在致命症状的方法。低剂量放射疗法(LD-RT)可诱导抗炎细胞因子反应,作为促炎细胞因子的抗衡,可能为 COVID-19 相关疾病提供治疗益处,这些疾病与发病率和死亡率显著相关。本研究将研究阳性免疫放射学反应,以确定它们是否可行、实用且能有效降低 COVID-19 关键阶段的危急炎症状况。本研究旨在探讨低剂量肺部放射治疗在细菌性和病毒性肺炎中的应用,并为 COVID-19 相关肺炎提供治疗方案。本文讨论了 LD-RT 理论在 COVID-19 患者中的证据。在 COVID-19 的不同阶段使用 LD-RT 似乎是有益的,其副作用比其他正在研究的治疗方法少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa3f/9921480/a210d2811448/40001_2023_999_Fig1_HTML.jpg

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