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佩吉特氏病。一种导致骨矿物质密度假性升高的病因。

Paget's disease. A cause of artificially elevated bone mineral density.

作者信息

Balseiro J, Eggli D F, Ziessman H A

机构信息

Department of Radiology, Georgetown University Hospital, Washington, D.C. 20007.

出版信息

Clin Nucl Med. 1987 Oct;12(10):809-10. doi: 10.1097/00003072-198710000-00012.

DOI:10.1097/00003072-198710000-00012
PMID:3677525
Abstract

A 48-year-old man with a ten-year history of corticosteroid-dependent asthma and a previous fracture of the right humerus after minimal trauma was referred for a dual photon absorptiometry (DPA) study to assess the degree of osteoporosis. The DPA study revealed a large discrepancy in bone mineral density (BMD) between the right and left hips. A Tc-99m MDP bone scan and an anteroposterior frog-leg radiograph demonstrated changes typical of Paget's disease in the sacrum, pelvis, and femurs. This case is an example of how underlying bone disease may artificially elevate bone mineral density, and demonstrates the value of performing BMD tests on both hips and the necessity for correlative bone scans and radiographs in selected cases.

摘要

一名48岁男性,有10年依赖皮质类固醇的哮喘病史,曾在轻微外伤后发生右肱骨骨折,因进行双能光子吸收测定(DPA)研究以评估骨质疏松程度而前来就诊。DPA研究显示左右髋部的骨矿物质密度(BMD)存在巨大差异。Tc-99m亚甲基二膦酸盐(MDP)骨扫描及前后位蛙式位X线片显示骶骨、骨盆和股骨有典型的佩吉特病改变。该病例表明潜在的骨病可能会人为地提高骨矿物质密度,并证明了对双侧髋部进行BMD检测的价值以及在特定病例中进行相关骨扫描和X线片检查的必要性。

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1
Paget's disease. A cause of artificially elevated bone mineral density.佩吉特氏病。一种导致骨矿物质密度假性升高的病因。
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Total body and regional bone mineral analysis by dual-photon absorptiometry in Paget's disease of bone.
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Effect of Paget's disease of bone on areal lumbar spine bone mineral density measured by DXA, and density of cortical and trabecular bone measured by quantitative CT.骨佩吉特病对通过双能X线吸收法测量的腰椎骨面积骨密度以及通过定量CT测量的皮质骨和小梁骨密度的影响。
Br J Radiol. 2000 Jul;73(871):720-6. doi: 10.1259/bjr.73.871.11089462.