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丙戊酸钠对光敏性癫痫的影响及其预后的对照研究。

A controlled study of the effect of sodium valproate on photosensitive epilepsy and its prognosis.

作者信息

Harding G F, Herrick C E, Jeavons P M

出版信息

Epilepsia. 1978 Dec;19(6):555-65. doi: 10.1111/j.1528-1157.1978.tb05036.x.

DOI:10.1111/j.1528-1157.1978.tb05036.x
PMID:367761
Abstract

The effect of sodium valproate on photosensitive epilepsy was studied. The range of flash rates of intermittent photic stimulation to which patients were sensitive (photosensitive range) was tested prior to treatment, and the reliability of this measure established by repeated tests on 70 patients. The photosensitive range was measured on 50 patients prior to and during treatment with sodium valproate. In 27 patients photosensitivity was abolished and in a further 12 patients photosensitivity was significantly reduced. A group of 167 patients followed without treatment did not show significant improvement over a 7 year period. Sixteen patients had drug treatment withdrawn, and in 7 months their photosensitive range had returned to its predrug level.

摘要

研究了丙戊酸钠对光敏性癫痫的影响。在治疗前测试了患者对间歇性光刺激敏感的闪光频率范围(光敏范围),并通过对70名患者的重复测试确定了该测量方法的可靠性。在50名患者使用丙戊酸钠治疗前和治疗期间测量了光敏范围。27名患者的光敏性消失,另有12名患者的光敏性显著降低。一组167名未经治疗的患者在7年期间未显示出明显改善。16名患者停止药物治疗,7个月后其光敏范围恢复到用药前水平。

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A controlled study of the effect of sodium valproate on photosensitive epilepsy and its prognosis.丙戊酸钠对光敏性癫痫的影响及其预后的对照研究。
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