A multivariable evoked potential measure applied to human epilepsy.

Based upon a three-dimensional plot (response plane) representing a condensation of human sensory evoked potential data obtained from a paired stimulus protocol, a study was undertaken to investigate electrophysiological changes following sodium valproate administration in subjects with photosensitive epilepsy. Initial results in two patients and two normal subjects suggest that the measure is reproducible and sensitive to electrophysiological changes accompanying anticonvulsant administration.