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体育活动对肥胖儿童和青少年心血管代谢疾病的益处。

Benefits of Physical Activity on Cardiometabolic Diseases in Obese Children and Adolescents.

作者信息

Gao Juan, Lu Yi, Gokulnath Priyanka, Vulugundam Gururaja, Li Guoping, Li Jin, Xiao Junjie

机构信息

Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong 226011, Jiangsu Province, China.

Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, Shanghai 200444, China.

出版信息

J Transl Int Med. 2022 Sep 30;10(3):236-245. doi: 10.2478/jtim-2022-0041. eCollection 2022 Sep.

Abstract

In the past few decades, obesity in the pediatric population has dramatically increased and is common in many countries. Childhood obesity often causes health problems and increases the risk of cardiometabolic diseases such as type 2 diabetes, nonalcohol fatty liver, and cardiovascular diseases. Obesity in young people has been closely associated with environmental, behavioral, and genetic defects, including the availability of high-energy and sugary food and beverages, sedentary behavior, and hereditary factors. Few drugs are currently available to treat obesity in children and adolescents because it is difficult to demonstrate the safety of these drugs on the growth and development of the youth. Lifestyle modifications, such as diet control and physical exercise, are the primary approaches for preventing and treating childhood obesity. Among them, physical activity is a crucial component. This review summarizes the epidemiology, cardiometabolic risk of obesity, therapeutic strategies, and the benefits of exercise on obesity-related chronic diseases in children and adolescents.

摘要

在过去几十年中,儿童肥胖率急剧上升,在许多国家都很常见。儿童肥胖常常引发健康问题,并增加患2型糖尿病、非酒精性脂肪肝和心血管疾病等心脏代谢疾病的风险。年轻人肥胖与环境、行为和基因缺陷密切相关,包括高能和高糖食品及饮料的可得性、久坐不动的行为以及遗传因素。目前几乎没有药物可用于治疗儿童和青少年肥胖,因为很难证明这些药物对青少年生长发育的安全性。生活方式的改变,如饮食控制和体育锻炼,是预防和治疗儿童肥胖的主要方法。其中,体育活动是一个关键组成部分。本综述总结了儿童和青少年肥胖的流行病学、心脏代谢风险、治疗策略以及运动对肥胖相关慢性病的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88e3/9901555/ebea82246357/jtim-10-236-g001.jpg

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