Chen Xiaoliang, Zeng Mengya, Chen Chen, Zhu Dan, Chen Li, Jiang Zuying
The Affiliated Chenzhou Hospital, Hengyang Medical School, University of South China, Chenzhou, China.
The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Front Cardiovasc Med. 2023 Jan 26;9:1031255. doi: 10.3389/fcvm.2022.1031255. eCollection 2022.
To evaluate the efficacy of Psycho-Cardiology therapy among patients with acute myocardial infarction (AMI) complicated with mild anxiety and depression.
Two hundred and fifty-six patients with AMI who were admitted to the Cardiovascular Department of Chenzhou First People's Hospital from January 2018 to January 2020 were selected as subjects, and randomly divided into the control group ( = 128) and the Psycho-Cardiology treatment group ( = 128). Prior to the intervention, the general clinical data of the enrolled patients, such as gender, age, comorbidities (hypertension, diabetes) and smoking history, were compared, which revealed no statistical differences between the two groups ( > 0.05). The control group was given routine treatments such as reperfusion and secondary prevention of coronary heart disease, while the treatment group was given Psycho-Cardiology intervention in addition to the aforementioned treatments.
No significant differences in PHQ-9 and GAD-7 scores were observed between the control and treatment groups at admission ( > 0.05). After the Psycho-Cardiology treatment, the PHQ-9 and GAD-7 scores of the treatment group decreased significantly. Based on the 1-year post-treatment comparison, the left ventricular ejection fraction was improved more significantly in the Psycho-Cardiology treatment group, showing statistical significance ( < 0.05). The treatment group exhibited statistically significantly low incidences of adverse cardiovascular events, such as recurrent angina pectoris, heart failure, malignant arrhythmia, recurrent myocardial infarction and death ( < 0.05).
Psycho-Cardiology therapy is remarkably efficacious in improving the anxiety, depression, cardiac function and reducing the occurrence of adverse cardiovascular events, which can better improve the long-term prognosis of patients with AMI compared to the traditional treatments.
评估心理心脏病学疗法对急性心肌梗死(AMI)合并轻度焦虑和抑郁患者的疗效。
选取2018年1月至2020年1月在郴州市第一人民医院心血管科住院的256例AMI患者作为研究对象,随机分为对照组( = 128)和心理心脏病学治疗组( = 128)。干预前,比较纳入患者的一般临床资料,如性别、年龄、合并症(高血压、糖尿病)和吸烟史,两组间无统计学差异( > 0.05)。对照组给予冠心病再灌注及二级预防等常规治疗,治疗组在上述治疗基础上给予心理心脏病学干预。
入院时,对照组和治疗组的PHQ - 9和GAD - 7评分无显著差异( > 0.05)。心理心脏病学治疗后,治疗组的PHQ - 9和GAD - 7评分显著降低。基于治疗后1年的比较,心理心脏病学治疗组的左心室射血分数改善更显著,具有统计学意义( < 0.05)。治疗组复发性心绞痛、心力衰竭、恶性心律失常、复发性心肌梗死和死亡等不良心血管事件的发生率显著较低( < 0.05)。
心理心脏病学疗法在改善焦虑、抑郁、心脏功能及降低不良心血管事件发生率方面疗效显著,与传统治疗相比,能更好地改善AMI患者的长期预后。