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一名儿科患者从静脉注射曲前列尼尔过渡到吸入用曲前列尼尔的住院治疗情况。

Inpatient Transition From Intravenous to Inhaled Treprostinil in a Pediatric Patient.

作者信息

Procaccini David, Delany Dennis, Self Abigail, Kane Patricia Lawrence, Coulson John D

机构信息

Department of Pharmacy (DP), The Johns Hopkins Hospital, Baltimore, MD.

Department of Anesthesiology & Critical Care Medicine (DD, AS), The Johns Hopkins Hospital, Baltimore, MD.

出版信息

J Pediatr Pharmacol Ther. 2023;28(1):102-107. doi: 10.5863/1551-6776-28.1.102. Epub 2023 Feb 3.

Abstract

We report a case of a 7-year old male with idiopathic pulmonary arterial hypertension, successfully transitioned from an intravenous infusion to inhaled treprostinil during inpatient admission, after his intentional removal of multiple central venous catheters. He had no clinical, echocardiographic, or serum biomarker evidence of loss of control of pulmonary arterial hypertension during the 4-day transition. The patient was discharged home without complications, and 3 weeks after discharge the patient's pulmonary hypertension remained well controlled per clinical and echocardiographic evidence, including a significantly improved 6-minute walk distance test.

摘要

我们报告一例7岁男性特发性肺动脉高压患者,在其故意拔除多根中心静脉导管后,于住院期间成功从静脉输注过渡到吸入曲前列尼尔治疗。在4天的过渡期间,他没有出现肺动脉高压控制不佳的临床、超声心动图或血清生物标志物证据。患者出院时无并发症,出院3周后,根据临床和超声心动图证据,患者的肺动脉高压仍得到良好控制,包括6分钟步行距离测试显著改善。

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Evaluation and classification of pulmonary arterial hypertension.肺动脉高压的评估与分类
J Thorac Dis. 2019 Sep;11(Suppl 14):S1789-S1799. doi: 10.21037/jtd.2019.08.54.
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An overview of the 6th World Symposium on Pulmonary Hypertension.第六届世界肺动脉高压研讨会综述。
Eur Respir J. 2019 Jan 24;53(1). doi: 10.1183/13993003.02148-2018. Print 2019 Jan.

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