College of Chemistry and Materials Science, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou, Guangdong 511443, PR China.
Shandong Zhiyong Chemical Industry Technology Research Institute Co. LTD, Weifang, Shandong 261108, PR China.
Org Biomol Chem. 2023 Mar 8;21(10):2059-2068. doi: 10.1039/d2ob02267b.
Triazene is one of the most versatile building blocks in organic synthesis. Generally, it is viewed as a safe equivalent of diazonium salt, thus immediately finding numerous applications in preparative chemistry and medicinal chemistry. Besides, it can be used as a removable directing group in C-H functionalization or play a smart role as a precursor for aryl cation/radical generation. In this review, we will highlight recent noteworthy developments in this field.
三氮烯是有机合成中用途最广泛的砌块之一。通常，它被视为重氮盐的安全替代品，因此在制备化学和药物化学中立即找到了许多应用。此外，它可用作 C-H 官能化中的可去除导向基团，或作为芳基阳离子/自由基生成的前体发挥巧妙作用。在这篇综述中，我们将重点介绍该领域的最新重要进展。
