Gadia M T, Natori N, Ramos L B, Ayyar D R, Skyler J S, Sosenko J M
Division of General Medicine, University of Miami School of Medicine, FL 33101.
Diabetes Care. 1987 Sep-Oct;10(5):613-6. doi: 10.2337/diacare.10.5.613.
We have examined associations between height and quantitative sensory, nerve-conduction, and clinical indices of diabetic peripheral neuropathy in adult diabetic patients. Vibratory sensitivity was strongly related to height when measurements were made with either the vibration sensitivity tester (P = .02) or the biothesiometer (P less than .01); however, there was no relation between thermal sensitivity (as measured with the thermal sensitivity tester) and height. The peroneal and posterior tibial motor nerve-conduction velocities were inversely related to height (P less than .05 for both). When age and diabetes duration were included as variables in multiple regression analyses, the associations with height became stronger. Clinical indices of peripheral neuropathy were also related to height in these analyses. Glycosylated hemoglobin was significantly related to thermal sensitivity and the peroneal and posterior tibial motor nerve-conduction velocities but not to vibratory sensitivity. These data indicate that height has a marked influence on quantitative sensory, nerve-conduction, and clinical indices of diabetic peripheral neuropathy.
我们研究了成年糖尿病患者身高与糖尿病周围神经病变的定量感觉、神经传导及临床指标之间的关联。使用振动敏感度测试仪（P = 0.02）或生物感觉阈值测定仪（P < 0.01）进行测量时，振动敏感度与身高密切相关；然而，热敏感度（用热敏感度测试仪测量）与身高之间无关联。腓总神经和胫后运动神经传导速度与身高呈负相关（两者P均< 0.05）。在多元回归分析中将年龄和糖尿病病程作为变量纳入时，与身高的关联变得更强。在这些分析中，周围神经病变的临床指标也与身高有关。糖化血红蛋白与热敏感度以及腓总神经和胫后运动神经传导速度显著相关，但与振动敏感度无关。这些数据表明，身高对糖尿病周围神经病变的定量感觉、神经传导及临床指标有显著影响。
