School of Medicine, University of St Andrews, St Andrews, UK.
Department of Speech and Hearing Sciences, University of New Mexico, Albuquerque, New Mexico, USA.
Child Dev. 2023 Jul-Aug;94(4):970-984. doi: 10.1111/cdev.13914. Epub 2023 Feb 13.
Handedness has been studied for association with language-related disorders because of its link with language hemispheric dominance. No clear pattern has emerged, possibly because of small samples, publication bias, and heterogeneous criteria across studies. Non-right-handedness (NRH) frequency was assessed in N = 2503 cases with reading and/or language impairment and N = 4316 sex-matched controls identified from 10 distinct cohorts (age range 6-19 years old; European ethnicity) using a priori set criteria. A meta-analysis (N = 1994) showed elevated NRH % in individuals with language/reading impairment compared with controls (OR = 1.21, CI = 1.06-1.39, p = .01). The association between reading/language impairments and NRH could result from shared pathways underlying brain lateralization, handedness, and cognitive functions.
已针对用手习惯与语言相关障碍之间的关系进行了研究，因为用手习惯与语言优势半球之间存在关联。由于样本较小、发表偏倚以及研究之间的标准存在差异，因此尚未得出明确的模式。从 10 个不同队列（年龄范围为 6-19 岁；欧洲种族）中确定了 2503 例阅读和/或语言障碍病例和 4316 名性别匹配的对照者，使用事先设定的标准评估非右利手（NRH）的频率。荟萃分析（N = 1994）显示，与对照组相比，语言/阅读障碍患者的 NRH%升高（OR = 1.21，CI = 1.06-1.39，p =.01）。阅读/语言障碍与 NRH 之间的关联可能源于大脑侧化、用手习惯和认知功能的基础上存在共同途径。
