Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Statistical Consulting Center, University of Pittsburgh, Pittsburgh, Pennsylvania.
Prehosp Emerg Care. 2024;28(2):209-214. doi: 10.1080/10903127.2023.2177366. Epub 2023 Feb 16.
We evaluated first-pass endotracheal intubation (ETI) success within the critical care transport (CCT) environment using a natural experiment created by the COVID-19 pandemic. Our primary objective was to evaluate if the use of personal protective equipment (PPE) or the COVID-19 time period was associated with differences in first-pass success rates of ETI within a large CCT system with a high baseline ETI first-pass success rate. We hypothesized that pandemic-related challenges would be associated with decreased first-pass success rates.
We performed a retrospective before-after cohort study of airway management by CCT personnel relative to the COVID-19 pandemic. We used a mixed effects logistic regression to evaluate the association between enhanced PPE (N95 mask, eye protection) use and the pandemic time period on first-pass intubation success, while controlling for other factors potentially associated with intubation success. Variables in the final model included patient demographics (age, sex, and race), body mass index, medical category (trauma versus non-trauma), interfacility or scene response, blade size (Macintosh 3 versus 4), use of face mask, use of eye protection, and crew member length of service.
We identified 1279 cases involving intubation attempts on adult patients during the study period. A total of 1133 cases were included in the final analysis, with an overall first-pass success rate of 95.7% (96.4% pre-COVID-19 and 94.8% during COVID-19). In our final mixed effects logistic regression model, enhanced PPE use and the COVID-19 time period were not associated with first-pass intubation success rate.
In a large regional CCT system with a high ETI first-pass success rate, neither PPE use nor the COVID-19 time period were associated with differences in ETI first-pass success while controlling for relevant patient and operational factors. Other emergency medical services (EMS) systems may have encountered different effects of pandemic-related PPE use on intubation success rates. Further studies are needed to evaluate the influence of sustained use of enhanced PPE or changes in training or procedural experience on post-pandemic ETI first-pass success rates for non-CCT EMS clinicians.
我们通过 COVID-19 大流行造成的自然实验,评估了重症监护转运(CCT)环境中的首次气管内插管(ETI)成功率。我们的主要目的是评估个人防护设备(PPE)的使用或 COVID-19 时期是否与高基线 ETI 首次通过成功率的大型 CCT 系统内 ETI 首次通过成功率的差异相关。我们假设与大流行相关的挑战与首次通过成功率降低有关。
我们对与 COVID-19 大流行相关的 CCT 人员的气道管理进行了回顾性前后队列研究。我们使用混合效应逻辑回归来评估增强型 PPE(N95 口罩、眼部保护)的使用与大流行时期对首次插管成功率的关联,同时控制其他可能与插管成功率相关的因素。最终模型中的变量包括患者人口统计学特征(年龄、性别和种族)、体重指数、医疗类别(创伤与非创伤)、院内或现场反应、叶片大小(Macintosh 3 与 4)、面罩使用、眼部保护使用和机组人员服务年限。
我们确定了研究期间涉及成年患者插管尝试的 1279 例病例。共有 1133 例病例纳入最终分析,总首次通过成功率为 95.7%(COVID-19 前为 96.4%,COVID-19 期间为 94.8%)。在我们最终的混合效应逻辑回归模型中,增强型 PPE 的使用和 COVID-19 时期与首次插管成功率无关。
在一个具有高 ETI 首次通过成功率的大型区域 CCT 系统中,在控制相关患者和操作因素的情况下,PPE 的使用或 COVID-19 时期与 ETI 首次通过成功率的差异无关。其他紧急医疗服务(EMS)系统可能遇到了与大流行相关的 PPE 使用对插管成功率的不同影响。需要进一步研究来评估持续使用增强型 PPE 或培训或程序经验的变化对非 CCT EMS 临床医生大流行后 ETI 首次通过成功率的影响。