Center for Infectious Disease Modeling and Analysis, Yale School of Public Health, New Haven, CT 06520.
The Laboratory of Chemical Physics, NIDDK, NIH, Bethesda, MD 20892.
Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2215424120. doi: 10.1073/pnas.2215424120. Epub 2023 Feb 13.
The Russian invasion of Ukraine on February 24, 2022, has displaced more than a quarter of the population. Assessing disease burdens among displaced people is instrumental in informing global public health and humanitarian aid efforts. We estimated the disease burden in Ukrainians displaced both within Ukraine and to other countries by combining a spatiotemporal model of forcible displacement with age- and gender-specific estimates of cardiovascular disease (CVD), diabetes, cancer, HIV, and tuberculosis (TB) in each of Ukraine's 629 raions (i.e., districts). Among displaced Ukrainians as of May 13, we estimated that more than 2.63 million have CVDs, at least 615,000 have diabetes, and over 98,500 have cancer. In addition, more than 86,000 forcibly displaced individuals are living with HIV, and approximately 13,500 have TB. We estimated that the disease prevalence among refugees was lower than the national disease prevalence before the invasion. Accounting for internal displacement and healthcare facilities impacted by the conflict, we estimated that the number of people per hospital has increased by more than two-fold in some areas. As regional healthcare systems come under increasing strain, these estimates can inform the allocation of critical resources under shifting disease burdens.
2022 年 2 月 24 日,俄罗斯对乌克兰的入侵导致超过四分之一的人口流离失所。评估流离失所者的疾病负担对于指导全球公共卫生和人道主义援助工作至关重要。我们通过将强制性流离失所的时空模型与乌克兰每个 629 个区(即行政区)的心血管疾病 (CVD)、糖尿病、癌症、艾滋病毒和结核病 (TB) 的年龄和性别特定估计值相结合,估计了在乌克兰境内和其他国家流离失所的乌克兰人所承受的疾病负担。截至 5 月 13 日,我们估计超过 263 万流离失所的乌克兰人患有 CVD,至少 61.5 万人患有糖尿病,超过 98500 人患有癌症。此外,超过 86000 名被迫流离失所的人感染了艾滋病毒,约有 13500 人患有结核病。我们估计难民的疾病流行率低于入侵前的全国疾病流行率。考虑到内部流离失所和受冲突影响的医疗设施,我们估计在某些地区,每个医院的人数增加了两倍多。随着区域医疗体系承受越来越大的压力,这些估计可以为不断变化的疾病负担下的关键资源分配提供信息。