Multi-stimuli-responsive molecular fluorescent probes for bioapplications.

Stimuli-responsive fluorescent probes have been widely utilized in detecting the physiological and pathological states of living systems. Numerous stimuli-responsive fluorescent probes have been developed due to their advantages of good sensitivity, high resolution, and high contrast fluorescent signals. In this feature article, the progress of multi-stimuli-responsive probes, including organic molecules and metal complexes, for the detection of various biomarkers for bio-applications is summarized. The feature article focuses on the applications of organic-molecule- and metal-complex-based molecular probes in biological systems for detecting different biomarkers of cancer or other diseases. The current challenges and potential future directions of these probes for applications in biological systems are also discussed.