Australia and New Zealand Dialysis and Transplant Registry, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Department of Nephrology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Am J Transplant. 2022 Mar;22(3):886-897. doi: 10.1111/ajt.16898. Epub 2021 Dec 13.
Deceased donor kidneys are a scarce community resource; therefore, the principles underpinning organ allocation should reflect societal values. This study aimed to elicit community and healthcare professional preferences for principles guiding the allocation of kidneys from deceased donors and compare how these differed across the populations. A best-worst scaling survey including 29 principles in a balanced incomplete block design was conducted among a representative sample of the general community (n = 1237) and healthcare professionals working in transplantation (n = 206). Sequential best-worst multinomial logistic regression was used to derive scaled preference scores (PS) (range 0-100). Thematic analysis of free text responses was performed. Five of the six most valued principles among members of the community related to equity, including priority for the longest waiting (PS 100), difficult to transplant (PS 94.5) and sickest (PS 93.9), and equitable access for men and women (PS 94.0), whereas the top four principles for healthcare professional focused on maximizing utility (PS 89.9-100). Latent class analysis identified unmeasured class membership among community members. There are discordant views between community members and healthcare professionals. These should be considered in the design, evaluation, and implementation of deceased donor kidney allocation protocols.
已故供体肾脏是一种稀缺的社区资源;因此,器官分配所依据的原则应反映社会价值观。本研究旨在了解社区和医疗保健专业人员对指导从已故供体分配肾脏的原则的偏好,并比较这些偏好在不同人群中的差异。在一个具有代表性的社区(n=1237)和从事移植工作的医疗保健专业人员(n=206)中,采用平衡不完全区块设计的最佳最差标度调查,包括 29 项原则。使用顺序最佳最差多项逻辑回归得出标度偏好得分(PS)(范围 0-100)。对自由文本回复进行主题分析。社区成员最看重的六个原则中的五个与公平有关,包括最长等待时间的优先权(PS100)、最难移植(PS94.5)和最病重(PS93.9),以及男女平等的准入(PS94.0),而医疗保健专业人员的前四个原则则侧重于最大限度地提高效用(PS89.9-100)。潜在类别分析确定了社区成员中存在未测量的类别成员。社区成员和医疗保健专业人员之间存在意见分歧。在制定、评估和实施已故供体肾脏分配方案时,应考虑这些意见分歧。