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经会阴前列腺根治性切除术与机器人辅助前列腺根治性切除术的肿瘤学和功能结局比较。

Comparison of oncological and functional outcomes of perineoscopic radical prostatectomy and robot-assisted radical prostatectomy.

机构信息

Urology, Mus State Hospital, Saray Mah., Yeni Hastane Cad., No:1/A, Muş Merkez, Turkey.

Department of Urology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Zuhuratbaba Mh. Tevfik Saglam Cd. No:11 Bakirkoy, Istanbul, Turkey.

出版信息

Updates Surg. 2023 Jun;75(4):1027-1035. doi: 10.1007/s13304-023-01453-3. Epub 2023 Feb 14.

DOI:10.1007/s13304-023-01453-3
PMID:36788157
Abstract

The aim of this study is to compare the functional, oncological, and complication outcomes of perineoscopic radical prostatectomy (PeRP) and robot-assisted radical prostatectomy (RARP) operations. Patients who underwent radical prostatectomy (RP) between October 2018 and June 2020 for localized prostate cancer (N0, < T3) were retrospectively screened. After the exclusion criteria, 56 patients who underwent PeRP and 67 patients who underwent RARP remained in the study. Demographic, perioperative, and postoperative data were collected. In functional outcomes, continence and potency status were compared at 1, 3, 6, and 12 months. The mean age of the patients was 61.3 ± 5.9 years in the PeRP group and 62.2 ± 5.7 years in the RARP group. No statistically significant differences were present between preoperative and postoperative values. Among the perioperative findings, the mean operation time was 90.4 ± 11.2 min for the PeRP group and 114.6 ± 14.7 min for the RARP group. The operation time was shorter in the PeRP group. The average hospital stay was 2 ± 0.6 days in the PeRP group and 2.3 ± 0.5 days in the RARP group. It was significantly shorter in the PeRP group. There is no statistically significant difference between the two groups in the oncological and functional results. PeRP is a surgical procedure safe in low-risk patients with medium-risk prostate cancer (PCa) who do not require lymph-node dissection. Moreover, PeRP minimizes the difficulties of perineal surgery.

摘要

本研究旨在比较经会阴前列腺根治切除术(PeRP)和机器人辅助前列腺根治切除术(RARP)的功能、肿瘤学和并发症结局。回顾性筛选了 2018 年 10 月至 2020 年 6 月期间因局限性前列腺癌(N0,<T3)接受根治性前列腺切除术(RP)的患者。排除标准后,共有 56 例接受 PeRP 和 67 例接受 RARP 的患者纳入研究。收集了人口统计学、围手术期和术后数据。在功能结局方面,在 1、3、6 和 12 个月时比较了尿控和勃起功能状态。PeRP 组患者的平均年龄为 61.3±5.9 岁,RARP 组为 62.2±5.7 岁。术前和术后值之间无统计学差异。在围手术期发现,PeRP 组的平均手术时间为 90.4±11.2 分钟,RARP 组为 114.6±14.7 分钟。PeRP 组手术时间更短。PeRP 组的平均住院时间为 2±0.6 天,RARP 组为 2.3±0.5 天。PeRP 组明显更短。两组在肿瘤学和功能结果方面无统计学差异。PeRP 是一种安全的手术程序,适用于不需要淋巴结清扫的中危前列腺癌(PCa)低危患者。此外,PeRP 最大限度地减少了会阴手术的难度。

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本文引用的文献

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The impact of surgical margin status on prostate cancer-specific mortality after radical prostatectomy: a systematic review and meta-analysis.根治性前列腺切除术后手术切缘状态对前列腺癌特异性死亡率的影响:系统评价和荟萃分析。
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Robot-assisted radical perineal prostatectomy: a review of 95 cases.机器人辅助经会阴前列腺根治术:95 例回顾。
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Positive surgical margin is associated with biochemical recurrence risk following radical prostatectomy: a meta-analysis from high-quality retrospective cohort studies.阳性切缘与根治性前列腺切除术后生化复发风险相关:来自高质量回顾性队列研究的荟萃分析。
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