Jamaluddin Jazlan, Jamil Siti Nuradliah
Family Medicine, Klinik Kesihatan Sauk, Kuala Kangsar, MYS.
Family Medicine, Klinik Kesihatan Pasir Gudang, Johor Bahru, MYS.
Cureus. 2023 Jan 11;15(1):e33657. doi: 10.7759/cureus.33657. eCollection 2023 Jan.
Irritant contact dermatitis (ICD) is a common skin condition in primary care. The frequent cause of ICD includes hair dye, nail polish, paints, cleaners, soap, and detergent. We present a case of ICD caused by topical garlic medicament, successfully identified and managed in primary care. A 20-year-old woman presented with a sudden onset of multiple painful localized blisters on the right antecubital fossa. She reported applying raw garlic paste to the area one day before the clinic visit to treat mild itchiness. She had no known allergies or medical illnesses. Otherwise, there were no rashes elsewhere or oral and genital ulcers. She was not on any regular medication or taking traditional medication. Examination revealed multiple bullae on the antecubital fossa with perilesional erythema. The lesion was sharply bordered within the contact areas, was asymmetric, and did not spread elsewhere. The clinical history of immediate bullae formation after direct contact with garlic was consistent with ICD due to garlic medicament. The lesions were managed with regular dressings. At one week follow-up, the lesions had healed well. She was advised to avoid further application of topical garlic medicines. Although Allium sativum (garlic) has been used either topical or orally as a medicinal treatment worldwide for thousands of years to treat various conditions, it still has the potential to cause irritant dermatitis when applied to skin and mucosa. Patients and healthcare providers should be cautious of the potential side effects, such as ICD, when using garlic for medicinal purposes.
刺激性接触性皮炎(ICD)是基层医疗中常见的皮肤疾病。ICD的常见病因包括染发剂、指甲油、油漆、清洁剂、肥皂和洗涤剂。我们报告一例由外用大蒜药物引起的ICD病例,在基层医疗中成功确诊并得到处理。一名20岁女性因右肘前窝突然出现多个疼痛性局限性水疱前来就诊。她报告在就诊前一天在该部位涂抹生大蒜糊以治疗轻度瘙痒。她无已知过敏史或内科疾病。此外,身体其他部位无皮疹,也无口腔和生殖器溃疡。她未服用任何常规药物或传统药物。检查发现肘前窝有多个大疱,周围有红斑。病变在接触区域边界清晰,不对称,未扩散至其他部位。直接接触大蒜后立即出现大疱的临床病史与大蒜药物引起的ICD相符。通过定期换药处理病变。在一周的随访中,病变愈合良好。建议她避免再次外用大蒜药物。尽管数千年来大蒜(Allium sativum)在全球范围内一直被外用或口服用于治疗各种疾病,但当应用于皮肤和黏膜时仍有可能引起刺激性皮炎。患者和医疗服务提供者在将大蒜用于药用目的时应警惕潜在的副作用,如ICD。