Sharma Sunakshi, Malgotra Vikas, Wani Mashkoor
Dermatology, Government Medical College, Jammu, IND.
Dermatology, Rama Medical College, Hapur, IND.
Cureus. 2023 Jan 11;15(1):e33641. doi: 10.7759/cureus.33641. eCollection 2023 Jan.
Kaposi sarcoma (KS) is a rare multifocal tumor originating from the cells lining the blood vessels. It is characterized by vascular proliferation and is usually associated with immunosuppression due to multiple factors, including AIDS or organ transplantation. However, sporadic cases of KS have been reported in HIV-negative immunocompetent patients. Paclitaxel has shown efficacy and may be an alternative for the initial therapy of patients with KS. We report a case of KS in a 70-year-old Asian male who was HIV-negative, with no history of immunosuppression or homosexuality and a good response to treatment with Paclitaxel.
卡波西肉瘤(KS)是一种罕见的多灶性肿瘤,起源于血管内衬细胞。其特征为血管增生,通常因多种因素导致免疫抑制而发生,这些因素包括艾滋病或器官移植。然而,在HIV阴性的免疫功能正常患者中也有散发性KS病例的报道。紫杉醇已显示出疗效,可能是KS患者初始治疗的一种选择。我们报告一例70岁亚洲男性的KS病例,该患者HIV阴性,无免疫抑制或同性恋史,对紫杉醇治疗反应良好。