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一种不寻常的肺部曲霉菌感染:支气管内曲菌球。

An Unusual Pulmonary Aspergillus Infection: Endobronchial Aspergilloma.

作者信息

Kuwal Ashok, Kochar Rishabh, Agarwal Rishabh

机构信息

Pulmonary Medicine, Dr. Sampurnanand Medical College and Associated Group of Hospitals, Jodhpur, IND.

Pulmonary Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, IND.

出版信息

Cureus. 2023 Jan 10;15(1):e33587. doi: 10.7759/cureus.33587. eCollection 2023 Jan.

DOI:10.7759/cureus.33587
PMID:36788918
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9910822/
Abstract

Endobronchial aspergilloma (EBA) is an extremely rare presentation of pulmonary involvement of Aspergillus. It is a noninvasive form of  where the fungus overgrows and colonizes the bronchial lumen. The patient may present with chronic cough, dyspnea, hemoptysis, or wheezing. The diagnosis is usually incidental when bronchoscopy is performed to evaluate the cause of hemoptysis or radiological abnormalities. Here, we report a case of a middle-aged female who presented with hemoptysis and right middle lobe collapse and was subsequently diagnosed to have EBA on bronchoscopy with endobronchial biopsy. Although EBA is rare, it should be considered as a differential in the evaluation of endobronchial mass lesions.

摘要

支气管曲菌球(EBA)是曲霉菌肺部感染极为罕见的一种表现形式。它是一种非侵袭性的形式,真菌在支气管腔内过度生长并定植。患者可能出现慢性咳嗽、呼吸困难、咯血或喘息。诊断通常是在进行支气管镜检查以评估咯血原因或放射学异常时偶然发现的。在此,我们报告一例中年女性患者,她因咯血和右中叶肺不张就诊,随后经支气管镜检查及支气管活检诊断为EBA。尽管EBA罕见,但在评估支气管内肿块病变时应将其列为鉴别诊断之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc75/9910822/d326328f1931/cureus-0015-00000033587-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc75/9910822/9daf9e2e15cc/cureus-0015-00000033587-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc75/9910822/3532e478915e/cureus-0015-00000033587-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc75/9910822/5a6e222ab668/cureus-0015-00000033587-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc75/9910822/d326328f1931/cureus-0015-00000033587-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc75/9910822/9daf9e2e15cc/cureus-0015-00000033587-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc75/9910822/3532e478915e/cureus-0015-00000033587-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc75/9910822/5a6e222ab668/cureus-0015-00000033587-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc75/9910822/d326328f1931/cureus-0015-00000033587-i04.jpg

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本文引用的文献

1
Endobronchial aspergilloma-a comprehensive literature review with focus on diagnosis and treatment modalities.支气管内曲霉菌病——全面文献复习,重点关注诊断和治疗方法。
Eur J Clin Microbiol Infect Dis. 2020 Apr;39(4):601-605. doi: 10.1007/s10096-019-03726-5. Epub 2019 Nov 18.
2
Endobronchial aspergilloma: A case report and literature review.支气管内曲菌球:一例报告及文献复习
Exp Ther Med. 2017 Jul;14(1):547-554. doi: 10.3892/etm.2017.4540. Epub 2017 Jun 1.
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Bronchomediastinal fistula caused by endobronchial aspergilloma.
支气管内曲菌球引起的支气管纵隔瘘。
Ann Am Thorac Soc. 2015 Jan;12(1):91-5. doi: 10.1513/AnnalsATS.201406-247BC.
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