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一例支气管内曲菌球合并肺腺癌病例。

A Case of Endobronchial Aspergilloma Coexisting With Lung Adenocarcinoma.

作者信息

El Hage Halim, Fagel Leon

机构信息

Pulmonary and Critical Care Medicine, Holy Redeemer Hospital and Medical Center, Meadowbrook, USA.

Pathology, Holy Redeemer Hospital and Medical Center, Meadowbrook, USA.

出版信息

Cureus. 2020 Nov 28;12(11):e11736. doi: 10.7759/cureus.11736.

Abstract

species can cause a variety of lung diseases. Endobronchial aspergilloma is a rare clinical entity rarely encountered and often not included in the classification of lung diseases.  An 82-year-old woman presented to the outpatient setting with wheezing, shortness of breath, and productive cough. CT of the chest showed the presence of airway enlargement in a finger in glove pattern in the right upper lobe suggestive of allergic bronchopulmonary aspergillosis. Despite adequate treatment the abnormality persisted on repeat imaging. Bronchoscopy with biopsies eventually revealed the presence of hyphal elements suggestive of and poorly differentiated adenocarcinoma. Endobronchial aspergilloma is rare and not included in the classification of lung diseases. It is thought to result from airway colonization by species. Occasionally it can obscure an underlying lung carcinoma and thus delay the diagnosis. Diagnosis is made by pathological examination of biopsy specimens. Optimal treatment is not well established.

摘要

某些物种可引发多种肺部疾病。支气管内曲菌球是一种罕见的临床病症,很少见且通常不被纳入肺部疾病分类中。一名82岁女性因喘息、气短和咳痰前来门诊就诊。胸部CT显示右上叶呈手套指样气道扩张,提示变应性支气管肺曲霉病。尽管进行了充分治疗,但复查影像时异常情况仍持续存在。支气管镜检查及活检最终发现有菌丝成分,提示低分化腺癌。支气管内曲菌球很罕见,未被纳入肺部疾病分类。它被认为是由某些物种在气道定植所致。偶尔它会掩盖潜在的肺癌,从而延误诊断。通过活检标本的病理检查进行诊断。最佳治疗方法尚未明确。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3992/7773290/5da843a7f3fc/cureus-0012-00000011736-i01.jpg

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