Scobbie R B, Sofaer J A
Dental School, University of Wales College of Medicine, Cardiff, UK.
Hum Hered. 1987;37(6):349-53. doi: 10.1159/000153733.
In 109 subjects from 50 families without major inherited disorders, sweat pore count showed the anticipated reduction with age but also unexpected systematic differences between sides and between fingers. After adjustment for age and sex, significant genetic variation was found for sweat pore count, hair density and tooth size. The three traits were not phenotypically correlated but there was a significant negative genetic correlation between hair density and sweat pore count. The findings suggest that the same genes influence these two traits in opposite directions and that genetic and environmental influences may act on them through different physiological mechanisms.
在来自50个无重大遗传性疾病家庭的109名受试者中，汗腺孔计数随年龄呈现预期的减少，但两侧之间以及手指之间也存在意外的系统性差异。在对年龄和性别进行调整后，发现汗腺孔计数、毛发密度和牙齿大小存在显著的遗传变异。这三个性状在表型上不相关，但毛发密度和汗腺孔计数之间存在显著的负遗传相关性。研究结果表明，相同的基因以相反的方向影响这两个性状，并且遗传和环境影响可能通过不同的生理机制作用于它们。
