ZBP1会引发感染了新冠病毒的肺部炎症。 - Suppr

Suppr

超能文献

ZBP1 inflames the SARS-CoV-2-infected lung.

作者信息

Yin Chaoran, Balachandran Siddharth

机构信息

Fox Chase Cancer Center, Philadelphia, PA, USA.

出版信息

Cell Res. 2023 May;33(5):333-334. doi: 10.1038/s41422-023-00784-5.

DOI:10.1038/s41422-023-00784-5

PMID:36792808

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9930697/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3461/10198256/31864795e72b/41422_2023_784_Fig1_HTML.jpg

相似文献

ZBP1 inflames the SARS-CoV-2-infected lung.

Cell Res. 2023 May;33(5):333-334. doi: 10.1038/s41422-023-00784-5.

SARS-CoV-2 Z-RNA activates the ZBP1-RIPK3 pathway to promote virus-induced inflammatory responses.

Cell Res. 2023 Mar;33(3):201-214. doi: 10.1038/s41422-022-00775-y. Epub 2023 Jan 17.

SARS-CoV-2 inflames the heart. The importance of awareness of myocardial injury in COVID-19 patients.

Int J Cardiol. 2020 Jul 15;311:122-123. doi: 10.1016/j.ijcard.2020.03.086. Epub 2020 Apr 6.

The next chapter for COVID-19: A respiratory virus inflames the brain.

Brain Behav Immun. 2022 Mar;101:286-287. doi: 10.1016/j.bbi.2022.01.017. Epub 2022 Jan 20.

Cytokines and Lipid Mediators of Inflammation in Lungs of SARS-CoV-2 Infected Mice.

Front Immunol. 2022 Jun 24;13:893792. doi: 10.3389/fimmu.2022.893792. eCollection 2022.

Infectious Clones Produce SARS-CoV-2 That Causes Severe Pulmonary Disease in Infected K18-Human ACE2 Mice.

mBio. 2021 Apr 20;12(2):e00819-21. doi: 10.1128/mBio.00819-21.

Lung Organoids as Model to Study SARS-CoV-2 Infection.

Cells. 2022 Sep 4;11(17):2758. doi: 10.3390/cells11172758.

Dysregulation of ion transport in the lung epithelium infected with SARS-CoV-2.

Am J Physiol Lung Cell Mol Physiol. 2021 Jun 1;320(6):L1183-L1185. doi: 10.1152/ajplung.00170.2021. Epub 2021 Apr 21.

SARS-CoV-2 activates lung epithelial cell proinflammatory signaling and leads to immune dysregulation in COVID-19 patients.

EBioMedicine. 2021 Aug;70:103500. doi: 10.1016/j.ebiom.2021.103500. Epub 2021 Jul 23.

Infection of lung megakaryocytes and platelets by SARS-CoV-2 anticipate fatal COVID-19.

Cell Mol Life Sci. 2022 Jun 16;79(7):365. doi: 10.1007/s00018-022-04318-x.

引用本文的文献

SARS-CoV-2 nsp15 enhances viral virulence by subverting host antiviral defenses.

Proc Natl Acad Sci U S A. 2025 Jun 17;122(24):e2426528122. doi: 10.1073/pnas.2426528122. Epub 2025 Jun 12.

Nucleic Acid Sensor-Mediated PANoptosis in Viral Infection.

Viruses. 2024 Jun 16;16(6):966. doi: 10.3390/v16060966.

本文引用的文献

Single-cell RNA sequencing reveals the developmental program underlying proximal-distal patterning of the human lung at the embryonic stage.

Cell Res. 2023 Jun;33(6):421-433. doi: 10.1038/s41422-023-00802-6. Epub 2023 Apr 21.

Z-RNA and the Flipside of the SARS Nsp13 Helicase: Is There a Role for Flipons in Coronavirus-Induced Pathology?

Front Immunol. 2022 Jun 17;13:912717. doi: 10.3389/fimmu.2022.912717. eCollection 2022.

Viral Z-RNA triggers ZBP1-dependent cell death.

Curr Opin Virol. 2021 Dec;51:134-140. doi: 10.1016/j.coviro.2021.10.004. Epub 2021 Oct 21.

Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract.

Nat Rev Microbiol. 2021 Jul;19(7):425-441. doi: 10.1038/s41579-021-00542-7. Epub 2021 Apr 6.

SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activation.

Signal Transduct Target Ther. 2020 Oct 9;5(1):235. doi: 10.1038/s41392-020-00334-0.

Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.

Cell. 2020 Mar 19;180(6):1115-1129.e13. doi: 10.1016/j.cell.2020.02.050.

RIPK3-driven cell death during virus infections.

Immunol Rev. 2017 May;277(1):90-101. doi: 10.1111/imr.12539.

An evolutionary perspective on the necroptotic pathway.

Trends Cell Biol. 2016 Oct;26(10):721-732. doi: 10.1016/j.tcb.2016.06.004. Epub 2016 Jun 28.

RIP3: a molecular switch for necrosis and inflammation.

Genes Dev. 2013 Aug 1;27(15):1640-9. doi: 10.1101/gad.223321.113.

DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.

Cell Host Microbe. 2012 Mar 15;11(3):290-7. doi: 10.1016/j.chom.2012.01.016.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

相似文献

ZBP1 inflames the SARS-CoV-2-infected lung.

Cell Res. 2023 May;33(5):333-334. doi: 10.1038/s41422-023-00784-5.

SARS-CoV-2 Z-RNA activates the ZBP1-RIPK3 pathway to promote virus-induced inflammatory responses.

Cell Res. 2023 Mar;33(3):201-214. doi: 10.1038/s41422-022-00775-y. Epub 2023 Jan 17.

SARS-CoV-2 inflames the heart. The importance of awareness of myocardial injury in COVID-19 patients.

Int J Cardiol. 2020 Jul 15;311:122-123. doi: 10.1016/j.ijcard.2020.03.086. Epub 2020 Apr 6.

The next chapter for COVID-19: A respiratory virus inflames the brain.

Brain Behav Immun. 2022 Mar;101:286-287. doi: 10.1016/j.bbi.2022.01.017. Epub 2022 Jan 20.

Cytokines and Lipid Mediators of Inflammation in Lungs of SARS-CoV-2 Infected Mice.

Front Immunol. 2022 Jun 24;13:893792. doi: 10.3389/fimmu.2022.893792. eCollection 2022.

Infectious Clones Produce SARS-CoV-2 That Causes Severe Pulmonary Disease in Infected K18-Human ACE2 Mice.

mBio. 2021 Apr 20;12(2):e00819-21. doi: 10.1128/mBio.00819-21.

Lung Organoids as Model to Study SARS-CoV-2 Infection.

Cells. 2022 Sep 4;11(17):2758. doi: 10.3390/cells11172758.

Dysregulation of ion transport in the lung epithelium infected with SARS-CoV-2.

Am J Physiol Lung Cell Mol Physiol. 2021 Jun 1;320(6):L1183-L1185. doi: 10.1152/ajplung.00170.2021. Epub 2021 Apr 21.

SARS-CoV-2 activates lung epithelial cell proinflammatory signaling and leads to immune dysregulation in COVID-19 patients.

EBioMedicine. 2021 Aug;70:103500. doi: 10.1016/j.ebiom.2021.103500. Epub 2021 Jul 23.

Infection of lung megakaryocytes and platelets by SARS-CoV-2 anticipate fatal COVID-19.

Cell Mol Life Sci. 2022 Jun 16;79(7):365. doi: 10.1007/s00018-022-04318-x.

引用本文的文献

SARS-CoV-2 nsp15 enhances viral virulence by subverting host antiviral defenses.

Proc Natl Acad Sci U S A. 2025 Jun 17;122(24):e2426528122. doi: 10.1073/pnas.2426528122. Epub 2025 Jun 12.

Nucleic Acid Sensor-Mediated PANoptosis in Viral Infection.

Viruses. 2024 Jun 16;16(6):966. doi: 10.3390/v16060966.

本文引用的文献

Single-cell RNA sequencing reveals the developmental program underlying proximal-distal patterning of the human lung at the embryonic stage.

Cell Res. 2023 Jun;33(6):421-433. doi: 10.1038/s41422-023-00802-6. Epub 2023 Apr 21.

Z-RNA and the Flipside of the SARS Nsp13 Helicase: Is There a Role for Flipons in Coronavirus-Induced Pathology?

Front Immunol. 2022 Jun 17;13:912717. doi: 10.3389/fimmu.2022.912717. eCollection 2022.

Viral Z-RNA triggers ZBP1-dependent cell death.

Curr Opin Virol. 2021 Dec;51:134-140. doi: 10.1016/j.coviro.2021.10.004. Epub 2021 Oct 21.

Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract.

Nat Rev Microbiol. 2021 Jul;19(7):425-441. doi: 10.1038/s41579-021-00542-7. Epub 2021 Apr 6.

SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activation.

Signal Transduct Target Ther. 2020 Oct 9;5(1):235. doi: 10.1038/s41392-020-00334-0.

Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.

Cell. 2020 Mar 19;180(6):1115-1129.e13. doi: 10.1016/j.cell.2020.02.050.

RIPK3-driven cell death during virus infections.

Immunol Rev. 2017 May;277(1):90-101. doi: 10.1111/imr.12539.

An evolutionary perspective on the necroptotic pathway.

Trends Cell Biol. 2016 Oct;26(10):721-732. doi: 10.1016/j.tcb.2016.06.004. Epub 2016 Jun 28.

RIP3: a molecular switch for necrosis and inflammation.

Genes Dev. 2013 Aug 1;27(15):1640-9. doi: 10.1101/gad.223321.113.

DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.

Cell Host Microbe. 2012 Mar 15;11(3):290-7. doi: 10.1016/j.chom.2012.01.016.