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社区药房是提高维生素D水平的关键。

Community pharmacy is the key to improving vitamin D levels.

作者信息

Lopez-Carmona F, Toro-Ruiz A, Gomez-Guzman M, Valverde-Merino M I, Piquer-Martinez C, Zarzuelo M J

机构信息

Pharmaceutical Care Research Group CTS-131, Faculty of Pharmacy, University of Granada, Spain.

Department of Pharmacology, Faculty of Pharmacy, University of Granada, Spain.

出版信息

Explor Res Clin Soc Pharm. 2023 Jan 18;9:100224. doi: 10.1016/j.rcsop.2023.100224. eCollection 2023 Mar.

DOI:10.1016/j.rcsop.2023.100224
PMID:36793797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9922955/
Abstract

INTRODUCTION

Vitamin D is an essential micronutrient that participates in the body's fundamental physiological processes. The pharmacist should involve the patient in his medication adherence, leading to a change in the patient's attitude towards his medication and towards his health problem, in order to achieve the pharmacological objective set.

METHODS

Quasi-experimental multicenter study design with non-probabilistic convenience sampling. A pharmacist-led intervention in health education was carried out, divided in two groups, face-to-face interview and on-line survey, and the results were evaluated 3 months later to observe if there was any change in the patient's health status or in their vitamin D levels.

RESULTS

The study was conducted in four pharmacies through face-to-face interviews ( = 49 patients) and online surveys ( = 23). Pharmaceutical intervention improved habits of exercise (0.81 ± 1.44 days/week face-to-face interviews vs -0.09 ± 2.35 days/week online surveys ( = 0.048)). In face-to-face interviews, consumption of vitamin D-rich foods was increased (0.55 unit of tuna/week; = 0.035 and 0.56 unit of avocado/week; = 0.001) and was improved correct intake of vitamin D supplements (32.5% baseline to 69.8% at 3 months). The increase in 25-hydroxyvitamin D levels (11.5 ng/mL after 3 months ( = 0.021)) was correlated to salmon consumption (0.951; = 0.013) and the improvement of quality of life was correlated to avocado consumption (1; < 0.001).

CONCLUSION

There are habits that improve vitamin D production such as increased physical activity, the correct use of vitamin D supplements and the consumption of foods with high vitamin D levels. The role of the pharmacist is crucial, involving the patient in the treatment making aware of the benefits for his/her health status of increasing vitamin D levels.

摘要

引言

维生素D是一种必需的微量营养素,参与人体基本生理过程。药剂师应促使患者坚持用药,从而改变患者对其用药及健康问题的态度,以实现既定的药理学目标。

方法

采用非概率便利抽样的准实验多中心研究设计。开展了一项由药剂师主导的健康教育干预,分为面对面访谈和在线调查两组,并在3个月后评估结果,以观察患者的健康状况或维生素D水平是否有任何变化。

结果

该研究在四家药店通过面对面访谈(n = 49例患者)和在线调查(n = 23例)进行。药物干预改善了运动习惯(面对面访谈组为0.81±1.44天/周,在线调查为-0.09±2.35天/周,P = 0.048)。在面对面访谈中,富含维生素D食物的摄入量增加(金枪鱼0.55份/周,P = 0.035;鳄梨0.56份/周,P = 0.001),维生素D补充剂的正确服用率提高(基线时为32.5%,3个月时为69.8%)。25-羟基维生素D水平的升高(3个月后升高11.5 ng/mL,P = 0.021)与三文鱼摄入量相关(r = 0.951,P = 0.013),生活质量的改善与鳄梨摄入量相关(r = 1,P < 0.001)。

结论

存在一些可改善维生素D生成的习惯,如增加体育活动、正确使用维生素D补充剂以及食用维生素D含量高的食物。药剂师的作用至关重要,促使患者参与治疗,使其意识到提高维生素D水平对其健康状况的益处。