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丙型肝炎病毒血清学阴性患者中与甲状腺功能减退相关的坏死松解性肢端红斑。

Necrolytic acral erythema associated with hypothyroidism in hepatitis C virus seronegative patient.

作者信息

Baroudi Ihsan, Alakhras Ola, Alkasem Alaa, Douri Thaer

机构信息

Faculty of Medicine University of Hama Hama Syria.

Department of Dermatology Al Assad Medical Center Hama Syria.

出版信息

Clin Case Rep. 2023 Feb 13;11(2):e6959. doi: 10.1002/ccr3.6959. eCollection 2023 Feb.

DOI:10.1002/ccr3.6959
PMID:36794036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9923471/
Abstract

Necrolytic acral erythema (NAE) is a rare cutaneous sign of hepatitis C virus (HCV), which generally presents as circumscribed keratotic plaques on the extremities. Many studies reported NAE in the absence of HCV. This case presents a female diagnosed with NAE and hypothyroidism in the absence of HCV infection.

摘要

坏死性肢端红斑(NAE)是丙型肝炎病毒(HCV)感染的一种罕见皮肤表现,通常表现为四肢的局限性角化性斑块。许多研究报道了无HCV感染情况下的NAE。本病例报告了一名女性,在无HCV感染的情况下被诊断为NAE和甲状腺功能减退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fb6/9923471/06ef4dc8876e/CCR3-11-e6959-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fb6/9923471/9ffe5e439a5b/CCR3-11-e6959-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fb6/9923471/7d49033938af/CCR3-11-e6959-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fb6/9923471/06ef4dc8876e/CCR3-11-e6959-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fb6/9923471/9ffe5e439a5b/CCR3-11-e6959-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fb6/9923471/7d49033938af/CCR3-11-e6959-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fb6/9923471/06ef4dc8876e/CCR3-11-e6959-g003.jpg

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本文引用的文献

1
Necrolytic Acral Erythema in Association With Hypothyroidism.与甲状腺功能减退相关的坏死性肢端红斑
JAMA Dermatol. 2020 Nov 1;156(11):1268-1270. doi: 10.1001/jamadermatol.2020.1976.
2
Necrolytic Acral Erythema in Seronegative Hepatitis C Patient with Vitamin B12 Deficiency.维生素B12缺乏的血清阴性丙型肝炎患者的坏死松解性肢端红斑
Indian Dermatol Online J. 2020 Mar 9;11(2):278-279. doi: 10.4103/idoj.IDOJ_398_19. eCollection 2020 Mar-Apr.
3
Necrolytic Acral Erythema: Current Insights.坏死性肢端红斑:当前见解
Clin Cosmet Investig Dermatol. 2020 Apr 5;13:275-281. doi: 10.2147/CCID.S189175. eCollection 2020.
4
Seronegative necrolytic acral erythema: A report of two cases and literature review.血清阴性坏死性肢端红斑:两例报告及文献复习
Indian Dermatol Online J. 2016 Jul-Aug;7(4):304-7. doi: 10.4103/2229-5178.185464.
5
Necrolytic Acral Erythema in the Absence of Hepatitis C Virus Infection.无丙型肝炎病毒感染时的坏死松解性肢端红斑
Indian J Dermatol. 2016 Jan-Feb;61(1):96-9. doi: 10.4103/0019-5154.174047.
6
Zinc deficiency associated with hypothyroidism: an overlooked cause of severe alopecia.与甲状腺功能减退相关的锌缺乏:严重脱发的一个被忽视的原因。
Int J Trichology. 2013 Jan;5(1):40-2. doi: 10.4103/0974-7753.114714.
7
Necrolytic acral erythema: a case not associated with hepatitis C infection.坏死松解性肢端红斑:一例与丙型肝炎感染无关的病例。
Dermatol Online J. 2008 Jun 15;14(6):10.