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肝上皮样血管平滑肌脂肪瘤呈散在分布,不适合手术切除:病例报告。

Hepatic epithelioid angiomyolipoma is scattered and unsuitable for surgery: a case report.

机构信息

Department of Emergency Surgery, Lu'an People's Hospital of Anhui Province, Lu'an, Anhui, China.

Department of Obstetrics and Gynaecology, Affiliated Hospital of Tongchuan City Maternal and Child Health Care, Tongchuan, Shaanxi, China.

出版信息

J Int Med Res. 2023 Feb;51(2):3000605231154657. doi: 10.1177/03000605231154657.

Abstract

Hepatic epithelioid angiomyolipoma (HEAML) is a rare tumour of mesenchymal tissue with a malignant tendency. Occurring most frequently in women, the relative incidence in men and women, according to incomplete statistics, is approximately 1:5. In rare cases, disease occurrence and development is hidden. Lesions are generally discovered as chance findings by patients; abdominal pain is the first symptom, and imaging has no specificity in diagnosing the disease. Therefore, great difficulties exist in the diagnosis and treatment of HEAML. Here, the case of a 51-year-old female patient with a history of hepatitis B, and abdominal pain over 8 months as the initial symptom, is described. The patient was found to have multiple intrahepatic angiomyolipoma. Due to the small and scattered foci, complete resection was impossible, and because of her history of hepatitis B, conservative treatment was undertaken, with the patient undergoing regular follow-up. When hepatic cell carcinoma could not be excluded, the patient was treated with transcatheter arterial chemoembolization. No tumour neogenesis or metastasis was detected at the 1-year follow-up.

摘要

肝上皮样血管平滑肌脂肪瘤(HEAML)是一种具有恶性倾向的间叶组织来源的罕见肿瘤。该病多见于女性,据不完全统计,男女发病比例约为 1:5。在极少数情况下,疾病的发生和发展是隐匿的。病变通常被患者偶然发现;腹痛是首发症状,影像学对该病的诊断缺乏特异性。因此,HEAML 的诊断和治疗存在很大困难。本文报道了 1 例 51 岁女性乙型肝炎病史患者,以腹痛 8 个月为首发症状。该患者被发现有多发性肝血管平滑肌脂肪瘤。由于病灶小且分散,无法完全切除,且由于患者有乙型肝炎病史,故进行了保守治疗,并定期随访。当不能排除肝细胞癌时,对患者行肝动脉化疗栓塞术治疗。在 1 年的随访中,未发现肿瘤新生或转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcfd/9936533/f4da511bd2e4/10.1177_03000605231154657-fig1.jpg

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