Unidade de Pesquisa Urogenital - Universidade do Estado do Rio de Janeiro - UERJ, Rio de Janeiro, RJ, Brasil.
Int Braz J Urol. 2023 Jul-Aug;49(4):428-440. doi: 10.1590/S1677-5538.IBJU.2023.9904.
To provide an overview of low-intensity extracorporeal shockwave therapy (LIEST) for erectile dysfunction (ED), pointing out which concepts are already consolidated and which paths we still need to advance.
We performed a narrative review of the literature on the role of shockwave therapies in erectile dysfunction, selecting publications in PUBMED, including only relevant clinical trials, systematic reviews and meta-analyses.
We found 11 studies (7 clinical trials, 3 systematic review and 1 meta-analysis) that evaluated the use of LIEST for the treatment of erectile dysfunction. One clinical trial evaluated the applicability in Peyronie's Disease and one other clinical trial evaluated the applicability after radical prostatectomy.
The literature presents little scientific evidence but suggests good results with the use of LIEST for ED. Despite a real optimism since it is a treatment modality capable of acting on the pathophysiology of ED, we must remain cautious, until a larger volume of higher quality studies allows us to establish which patient profile, type of energy and application protocol will achieve clinically satisfactory results.
概述低强度体外冲击波疗法(LIEST)治疗勃起功能障碍(ED),指出哪些概念已经得到巩固,哪些途径我们仍需推进。
我们对冲击波疗法治疗勃起功能障碍的作用进行了文献综述,在 PUBMED 上选择了相关的临床研究,包括仅相关的临床试验、系统评价和荟萃分析。
我们发现了 11 项研究(7 项临床试验、3 项系统评价和 1 项荟萃分析),评估了 LIEST 治疗勃起功能障碍的应用。一项临床试验评估了其在 Peyronie 病中的适用性,另一项临床试验评估了其在根治性前列腺切除术后的适用性。
文献提供的科学证据很少,但表明 LIEST 治疗 ED 有良好的效果。尽管由于它是一种能够作用于 ED 病理生理学的治疗方式,因此存在真正的乐观情绪,但我们必须保持谨慎,直到有更多高质量的研究能够确定哪种患者特征、能量类型和应用方案将获得临床满意的结果。