Tipping the Balance of Ubiquitination toward a Therapy for COVID-19.
作者信息
Morrell Eric D
机构信息
Division of Pulmonary, Critical Care, and Sleep Medicine University of Washington Seattle, Washington.
出版信息
Am J Respir Cell Mol Biol. 2023 May;68(5):480-481. doi: 10.1165/rcmb.2023-0020ED.
Abstract
摘要
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Am J Respir Cell Mol Biol. 2023 May;68(5):480-481. doi: 10.1165/rcmb.2023-0020ED.
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本文引用的文献
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Inhibiting the Deubiquitinase UCHL1 Reduces SARS-CoV-2 Viral Uptake by ACE2.抑制去泛素化酶 UCHL1 可减少 ACE2 介导的 SARS-CoV-2 病毒摄取。
Am J Respir Cell Mol Biol. 2023 May;68(5):566-576. doi: 10.1165/rcmb.2022-0331OC.
2
Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2.通过 MT1-MMP 介导的 ACE2 脱落来控制 SARS-CoV-2 感染。
Nat Commun. 2022 Dec 23;13(1):7907. doi: 10.1038/s41467-022-35590-x.
3
SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19.SARS-CoV-2 刺突蛋白增强 COVID-19 中 MAP4K3/GLK 诱导的 ACE2 稳定性。
EMBO Mol Med. 2022 Sep 7;14(9):e15904. doi: 10.15252/emmm.202215904. Epub 2022 Jul 27.
4
Degradation of SARS-CoV-2 receptor ACE2 by the E3 ubiquitin ligase Skp2 in lung epithelial cells.肺上皮细胞中 E3 泛素连接酶 Skp2 介导的 SARS-CoV-2 受体 ACE2 降解。
Front Med. 2021 Apr;15(2):252-263. doi: 10.1007/s11684-021-0837-6. Epub 2021 Jan 29.
5
SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis.SARS-CoV-2 通过网格蛋白介导的内吞作用感染细胞。
J Biol Chem. 2021 Jan-Jun;296:100306. doi: 10.1016/j.jbc.2021.100306. Epub 2021 Jan 19.
6
Targeting ACE2 for COVID-19 Therapy: Opportunities and Challenges.针对 COVID-19 治疗的 ACE2 靶点：机遇与挑战。
Am J Respir Cell Mol Biol. 2021 Apr;64(4):416-425. doi: 10.1165/rcmb.2020-0322PS.
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Human recombinant soluble ACE2 in severe COVID-19.严重新型冠状病毒肺炎中的人重组可溶性血管紧张素转换酶2
Lancet Respir Med. 2020 Nov;8(11):1154-1158. doi: 10.1016/S2213-2600(20)30418-5. Epub 2020 Sep 24.
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MDM2-Mediated Ubiquitination of Angiotensin-Converting Enzyme 2 Contributes to the Development of Pulmonary Arterial Hypertension.MDM2 介导的血管紧张素转换酶 2 泛素化参与肺动脉高压的发生。
Circulation. 2020 Sep 22;142(12):1190-1204. doi: 10.1161/CIRCULATIONAHA.120.048191. Epub 2020 Jul 28.
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A pneumonia outbreak associated with a new coronavirus of probable bat origin.一种新型冠状病毒引发的肺炎疫情，该病毒可能来源于蝙蝠。
Nature. 2020 Mar;579(7798):270-273. doi: 10.1038/s41586-020-2012-7. Epub 2020 Feb 3.
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