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伊维菌素在新冠治疗中的应用现状

Current status of usage of ivermectin in the management of COVID.

作者信息

Ilangovan Swetha, Ganapathy Dhanraj, Ahmed Nabeel, Pandurangan Kiran Kumar, Maiti Subhabrata

机构信息

Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.

出版信息

J Adv Pharm Technol Res. 2022 Dec;13(Suppl 2):S407-S411. doi: 10.4103/japtr.japtr_344_22. Epub 2022 Dec 30.

Abstract

The antibacterial, antiviral, and anticancer properties of ivermectin make it a wonder drug with a wide range of possible applications. It works against a variety of microorganisms, including viruses. Ivermectin has a wide range of antiviral effects, according to research in animal models. Because ivermectin is involved in a range of biological processes, it could be a promising therapeutic candidate for viruses such as COVID-19 and other positive-sense single-stranded RNA viruses. The study aims to analyze the awareness about the current status of usage of ivermectin in management of COVID among students studying in a private dental college. A study based on questionnaire was organized among students studying in a private dental college in Tamil Nadu. The subjects were asked a series of structural questions based on the usage of ivermectin in management of COVID. The questionnaire was prepared with 10 questions. 150 individuals completed the questionnaire; all of their answers were tallied in excel and imported into SPSS. For statistical analysis, the Chi-square test was performed. Excel was used to tabulate and enter the data, and the SPSS package software was used to analyze it. The study's threshold for statistical significance was set at < 0.05. From this study, we found that the students had limited knowledge about the usage of ivermectin for management of COVID. More studies should be conducted to widen the knowledge among the students about the current affairs of the world.

摘要

伊维菌素的抗菌、抗病毒和抗癌特性使其成为一种具有广泛潜在应用的神奇药物。它对多种微生物有效,包括病毒。根据动物模型研究,伊维菌素有广泛的抗病毒作用。由于伊维菌素参与一系列生物过程,它可能是治疗新冠病毒(COVID-19)等正链单链RNA病毒的有前景的候选药物。该研究旨在分析在一所私立牙科学院就读的学生对伊维菌素在新冠治疗中使用现状的认知情况。在泰米尔纳德邦一所私立牙科学院的学生中组织了一项基于问卷的研究。根据伊维菌素在新冠治疗中的使用情况,向受试者询问了一系列结构化问题。问卷设置了10个问题。150人完成了问卷;他们所有的答案都在Excel中进行了统计,并导入到SPSS中。为进行统计分析,采用了卡方检验。使用Excel对数据进行制表和录入,使用SPSS软件包对其进行分析。该研究的统计显著性阈值设定为<0.05。通过这项研究,我们发现学生对伊维菌素用于新冠治疗的使用情况了解有限。应该进行更多研究,以拓宽学生对世界时事的了解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bc2/9926582/c5785ad0cb06/JAPTR-13-407-g001.jpg

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