Barros Leandro S A, Castillo José M, Lacerda Heloísa R
Postgraduate Program in Tropical Medicine, Universidade Federal de Pernambuco, Recife, Brazil.
Department of Cardiology, Hospital Agamenon Magalhães, Recife, Brazil.
Echocardiography. 2023 Mar;40(3):227-234. doi: 10.1111/echo.15538. Epub 2023 Feb 17.
Right ventricular (RV) echocardiographic changes such as dilation or systolic dysfunction, and pulmonary arterial hypertension were observed in patients with COVID-19. The aim of our study was to determine the frequency of RV echocardiographic changes in patients who have recovered from COVID-19 and to verify the association between severe acute respiratory syndrome (SARS) and echocardiographic findings.
Patients who had recovered from COVID-19 undergoing outpatient follow-up underwent transthoracic echocardiography, and based on the findings, were divided into two groups: normal and abnormal. It was then verified whether there is an association between SARS and RV echocardiographic abnormalities in recovered patients.
The study included 61 patients, with a mean age of 54.2 ± 12.0 years, 57.4% had presented with SARS. The mean period of time between COVID-19 and the echocardiographic examination was 11.9 ± 7.0 months. Patients presented normal left ventricular systolic function. The frequency of RV echocardiographic changes in patients who had recovered from COVID-19 was 44.3%. RV systolic dysfunction was identified in 31.1%, followed by ventricular dilation in 14.7% and pulmonary hypertension in 9.8%. An association was observed between SARS and RV echocardiographic changes in recovered patients during outpatient follow-up (OR: 4.96; 95% CI: 1.37-17.9; p = 0.015). An association was also demonstrated between SARS and RV dilation (p = 0.007) and between SARS and systolic dysfunction (p = 0.028).
SARS is a risk factor for abnormal RV echocardiographic findings in patients recovered from COVID-19.
在新型冠状病毒肺炎（COVID-19）患者中观察到右心室（RV）超声心动图改变，如扩张或收缩功能障碍以及肺动脉高压。我们研究的目的是确定COVID-19康复患者中RV超声心动图改变的频率，并验证严重急性呼吸综合征（SARS）与超声心动图结果之间的关联。
对COVID-19康复后接受门诊随访的患者进行经胸超声心动图检查，并根据检查结果分为两组：正常组和异常组。然后验证康复患者中SARS与RV超声心动图异常之间是否存在关联。
该研究纳入了61例患者，平均年龄为54.2±12.0岁，57.4%的患者曾出现SARS。COVID-19与超声心动图检查之间的平均时间为11.9±7.0个月。患者左心室收缩功能正常。COVID-19康复患者中RV超声心动图改变的频率为44.3%。31.1%的患者存在RV收缩功能障碍，其次是14.7%的心室扩张和9.8%的肺动脉高压。在门诊随访期间，观察到康复患者中SARS与RV超声心动图改变之间存在关联（比值比：4.96；95%置信区间：1.37 - 17.9；p = 0.015）。还证明了SARS与RV扩张之间（p = 0.007）以及SARS与收缩功能障碍之间（p = 0.028）存在关联。
SARS是COVID-19康复患者RV超声心动图异常结果的一个危险因素。
