Wang Jin, Yang Dongmei, Cao Cheng
Department of Echocardiography, The First Affiliated Hospital of University of Science and Technology of China (USTC), Hefei, CHN.
Department of Cardiology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Hefei, CHN.
Cureus. 2024 Mar 3;16(3):e55432. doi: 10.7759/cureus.55432. eCollection 2024 Mar.
Background The current study aimed to examine the association between baseline clinical and echocardiographic parameters with new-onset coronavirus disease 2019 (COVID-19) infection. Methodology We retrospectively enrolled consecutive hospitalized patients from our center during the national outbreak of the COVID-19 pandemic in China. Overall, 100 patients were enrolled, including 38 patients with COVID-19 infection. Results Compared with those without infection, patients with COVID-19 infection were more likely male (63.2% vs. 35.5%, p = 0.008), were older (59.08 vs. 52.35 years, p = 0.022), had higher heart failure (31.6% vs. 11.3%, p = 0.018) and hypertension (52.6% vs. 30.6%, p = 0.036) rates, had lower left ventricular ejection fraction (LVEF) (61.16% vs. 65.76%, p = 0.018), had higher A-wave velocity (86.84 vs. 73.63 cm/s, p = 0.003), and had and lower E/A ratio (0.85 vs 1.04, p = 0.015). On univariate and multivariate analysis, baseline echocardiographic parameters (LVEF and A-wave velocity) were independent risk factors for COVID-19 infection. There were no significant changes in echocardiographic parameters during the one-month follow-up period in patients infected and not infected with COVID-19. Conclusions In conclusion, baseline echocardiographic parameters were significantly associated with acute COVID-19 infection.
背景 本研究旨在探讨基线临床和超声心动图参数与新型冠状病毒肺炎（COVID-19）新发感染之间的关联。方法 我们回顾性纳入了在中国COVID-19大流行全国爆发期间，来自本中心的连续住院患者。总共纳入了100例患者，其中包括38例COVID-19感染患者。结果 与未感染患者相比，COVID-19感染患者男性比例更高（63.2% 对35.5%，p = 0.008），年龄更大（59.08岁对52.35岁，p = 0.022），心力衰竭（31.6% 对11.3%，p = 0.018）和高血压（52.6% 对30.6%，p = 0.036）发生率更高，左心室射血分数（LVEF）更低（61.16% 对65.76%，p = 0.018），A波速度更高（86.84对73.63 cm/s，p = 0.003），E/A比值更低（0.85对1.04，p = 0.015）。单因素和多因素分析显示，基线超声心动图参数（LVEF和A波速度）是COVID-19感染的独立危险因素。在感染和未感染COVID-19的患者中，随访1个月期间超声心动图参数无显著变化。结论 总之，基线超声心动图参数与急性COVID-19感染显著相关。
