School of Pharmacy, Hangzhou Normal University, China.
Department of Biosystems Engineering, Biosensors National Special Lab, Zhejiang University, China.
Talanta. 2023 May 15;257:124368. doi: 10.1016/j.talanta.2023.124368. Epub 2023 Feb 15.
In this work, we developed a facile method to fabricate laser induced versatile graphene-metal nanoparticles (LIG-MNPs) electrodes with redox molecules sensing capabilities. Unlike conventional post-electrodes deposition, versatile graphene-based composites were engraved by a facile synthesis process. As a general protocol, we successfully prepared modular electrodes including LIG-PtNPs and LIG-AuNPs and applied them to electrochemical sensing. This facile laser engraving process enables rapid preparation and modification of electrodes, as well as simple replacement of metal particles modification towards varied sensing targets. The LIG-MNPs showed high sensitivity towards HO and HS due to their excellent electron transmission efficiency and electrocatalytic activity. By simply changing the types of coated precursors, the LIG-MNPs electrodes have successfully achieved real-time monitoring of HO released from tumor cells and HS contained in wastewater. This work contributed a universal and versatile protocol for quantitatively detecting a wide range of hazardous redox molecules.
在这项工作中，我们开发了一种简便的方法来制备具有氧化还原分子传感能力的激光诱导多功能石墨烯-金属纳米粒子（LIG-MNPs）电极。与传统的电极后沉积方法不同，我们通过一种简便的合成工艺来刻蚀多功能基于石墨烯的复合材料。作为一种通用方案，我们成功制备了包括 LIG-PtNPs 和 LIG-AuNPs 的模块化电极，并将其应用于电化学传感。这种简便的激光雕刻工艺能够实现电极的快速制备和修饰，以及金属颗粒修饰的简单替换，以满足各种传感目标的需求。由于其出色的电子传输效率和电催化活性，LIG-MNPs 对 HO 和 HS 表现出高灵敏度。通过简单改变涂层前体的类型，LIG-MNPs 电极成功实现了对肿瘤细胞释放的 HO 和废水中含有的 HS 的实时监测。这项工作为定量检测广泛的危险氧化还原分子提供了一种通用且多功能的方案。
