Department of Pathology, Guiqian International General Hospital, Guiyang, Guizhou Province, China.
Department of Laboratory Medicine, Guiqian International General Hospital, Guiyang, Guizhou Province, China.
Int J Surg Pathol. 2023 Sep;31(6):1132-1138. doi: 10.1177/10668969231152582. Epub 2023 Feb 19.
Gut-associated lymphoid tissue (GALT) carcinoma, also termed dome-type carcinoma, is an infrequent distinctive subtype of colorectal adenocarcinoma and only 18 cases have been reported in the English medical literature. These tumors have unique clinicopathological features and are considered to have a low malignant potential with favorable prognosis. Herein, we described a case of a 49-year-old male with intermittent hematochezia for 2 years. Colonoscopy revealed a sessile broad-based polyp of approximately 20 mm × 17 mm in the sigmoid colon 260 mm away from the anus, with a slightly hyperemic surface. Histologically, this lesion showed typical GALT carcinoma. The patient was followed up for one and a half year and he did not experience any discomfort, such as abdominal pain or hematochezia, and no tumor recurrence occurred. Moreover, we reviewed the literature, summarized the clinicopathological features of GALT carcinoma, and highlighted its pathological differential diagnosis to further explore this infrequent type of colorectal adenocarcinoma.
肠相关淋巴组织（GALT）癌，也称为穹窿型癌，是一种罕见的结直肠腺癌特殊亚型，仅在英文医学文献中报道了 18 例。这些肿瘤具有独特的临床病理特征，被认为恶性潜能低，预后良好。在此，我们描述了一例 49 岁男性间断便血 2 年。结肠镜检查显示距肛门 260mm 的乙状结肠有一约 20mm×17mm 的无蒂宽基息肉，表面稍充血。组织学上，该病变表现为典型的 GALT 癌。患者随访 1 年半，未出现腹痛或便血等不适，也未发生肿瘤复发。此外，我们复习了文献，总结了 GALT 癌的临床病理特征，并强调了其病理鉴别诊断，以进一步探讨这种罕见的结直肠腺癌。
