Department of Community Health and Epidemiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Hum Vaccin Immunother. 2023 Dec 31;19(1):2176640. doi: 10.1080/21645515.2023.2176640. Epub 2023 Feb 20.
Human Papillomavirus (HPV) is a highly contagious sexually transmitted infection that leads to preventable cancers of the mouth, throat, cervix, and genitalia. Despite the wide availability of HPV Vaccine (HPVV) in Canada, its uptake remains suboptimal. This review aims to identify factors (barriers and facilitators) in HPV vaccine uptake across English Canada at three levels (provider, system, and patient). We explored academic and gray literature to examine factors involved in HPVV uptake and synthesized results based on interpretive content analysis. The review identified the following factors of prime significance in the uptake of the HPV vaccine (a) at the provider level, 'acceptability' of the HPV vaccine, and 'appropriateness' of an intervention (b) at the patient level, the 'ability to perceive' and 'knowledge sufficiency' (c) at the system level, 'attitudes' of different players in vaccine programming, planning and delivery. Further research is needed to conduct population health intervention research in this area.
人乳头瘤病毒（HPV）是一种高度传染性的性传播感染，可导致口腔、喉咙、子宫颈和生殖器的可预防癌症。尽管 HPV 疫苗（HPVV）在加拿大广泛可用，但接种率仍不理想。本综述旨在确定在加拿大英语地区（在提供者、系统和患者三个层面上），HPV 疫苗接种的因素（障碍和促进因素）。我们探讨了学术和灰色文献，以研究 HPV 疫苗接种中涉及的因素，并根据解释性内容分析综合结果。该综述确定了 HPV 疫苗接种的以下主要因素：（a）在提供者层面上，HPV 疫苗的“可接受性”和干预措施的“适当性”；（b）在患者层面上，“感知能力”和“知识充足性”；（c）在系统层面上，疫苗规划、计划和交付中不同参与者的“态度”。在这一领域需要进一步研究以开展人群健康干预研究。
