中国老年癌症患者慢性疼痛与虚弱的路径模型：睡眠的中介作用
A pathway model of chronic pain and frailty in older Chinese cancer patients: The mediating effect of sleep.
作者信息
Zhang Qin, Yu Ming, Tang Rongrong, Wang Hui, Xiao Mingbing, Geng Guiling, Xie Juan, Yan Haiou
机构信息
Department of Oncology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China.
Department of Science and Technology, Affiliated Hospital of Nantong University, Nantong 226001, China.
出版信息
Geriatr Nurs. 2023 Mar-Apr;50:215-221. doi: 10.1016/j.gerinurse.2023.01.015. Epub 2023 Feb 17.
This study aimed to explore the association between chronic pain, sleep quality, and frailty, and whether sleep quality will mediate the relationship between chronic pain and frailty. A cross-sectional study was conducted between June 2020 and July 2021 among 308 patients in Nantong city. The relationship between chronic pain and frailty was tested using linear regression. The bootstrap method was used to examine mediating effect of sleep quality. Chronic pain was significantly correlated with frailty (r=0.271, P<.001). Sleep quality played a partially mediating role between chronic pain and frailty (β=0.160, R=32%, P<.001). Interventions to scientifically manage chronic pain and improve sleep quality may be effective in reducing the incidence of frailty in elderly cancer patients.
本研究旨在探讨慢性疼痛、睡眠质量与衰弱之间的关联，以及睡眠质量是否会介导慢性疼痛与衰弱之间的关系。2020年6月至2021年7月期间，在南通市的308例患者中进行了一项横断面研究。采用线性回归检验慢性疼痛与衰弱之间的关系。采用Bootstrap法检验睡眠质量的中介作用。慢性疼痛与衰弱显著相关（r=0.271，P<0.001）。睡眠质量在慢性疼痛与衰弱之间起部分中介作用（β=0.160，R=32%，P<0.001）。科学管理慢性疼痛和改善睡眠质量的干预措施可能有助于降低老年癌症患者衰弱的发生率。
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